Space Environment, Cosmic Radiations, Human Risk, Super-SCID-Human Mice, Transgenerational Effects, Parabolic Flight, Cancer Prevention, Behavior, Changes in Gene Expression
その他のタイトル（英）
Evaluation of Human Risk in Space Environment and Its Protection
National Institute of Biomedical Innovation
National Institute of Biomedical Innovation
National Institute of Biomedical Innovation
National Institute of Biomedical Innovation
National Institute of Biomedical Innovation
National Institute of Biomedical Innovation
National Institute of Biomedical Innovation
Graduate School of Medicine, Osaka University
Graduate School of Medicine, Osaka University
Institute of Science and Technology and Atomic Energy Research Institute, Faculty of Science and Engineering, Kinki University
出版者
宇宙航空研究開発機構宇宙科学研究所 (JAXA)(ISAS)
出版者（英）
Institute of Space and Astronautical Science, Japan Aerospace Exploration Agency (JAXA)(ISAS)
雑誌名
宇宙利用シンポジウム: 第27回: 平成22年度
雑誌名(英)
Space Utilization Research, Vol. 27 2011: Proceedings of The Twenty-seventh Space Utilization Symposium
The Twenty-seventh Space Utilization Symposium (January 24-25, 2011. Institute of Space and Astronautical Science, Japan Aerospace Exploration Agency (JAXA)(ISAS)), Sagamihara, Kanagawa Japan
抄録（英）
To study the human risk of cosmic environment (including neutrons) in the flying body and space base, (1) Morphological and functional effects (including changes in gene expression) of fission neutrons on human thyroid tissues maintained in super-SCID (severe combined immunodeficient) mice, (2) Microsatellite mutations and leukemia in the offspring of mice in the space environment, and (3) Protection of radiation-induced defects by food and supplement, and effects of space environment (including micro-gravity) on human diseases are carried out by using specific mouse models. The first two projects are ready to be carried out in the space environment, although these were cancelled in Japan (and also in USA and EU). As for Project 3, we demonstrated protection of leukemia and congenital anomalies by AHCC (Active Hexose Correlated Compound) treatment, and strong effects of micro-gravity (microG) on behavior and gene expression by parabolic flight were shown with panic mouse model.
内容記述
著者人数: 14人
形態: カラー図版あり
内容記述（英）
Number of authors: 14
Physical characteristics: Original contains color illustrations
宇宙環境の人体影響評価と防護に関する研究
65129040.pdf
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