Institute for Amphibian Biology, Graduate School Science, Hiroshima University
Institute for Amphibian Biology, Graduate School Science, Hiroshima University
Institute for Amphibian Biology, Graduate School Science, Hiroshima University
Institute for Amphibian Biology, Graduate School Science, Hiroshima University
Institute for Amphibian Biology, Graduate School Science, Hiroshima University
Institute for Amphibian Biology, Graduate School Science, Hiroshima University
Faculty of Pharmacy, Osaka Ohtani University
Institute of Space and Astronautical Science, Japan Aerospace Exploration Agency (JAXA)(ISAS)
Faculty of Integrated Arts and Sciences, Tokushima University
Redox Regulation Research Group, Tokyo Metropolitan Institute of Gerontology
出版者
宇宙航空研究開発機構宇宙科学研究本部
出版者（英）
Institute of Space and Astronautical Science, Japan Aerospace Exploration Agency (JAXA)
雑誌名
宇宙利用シンポジウム
雑誌名(英)
Space Utilization Research: Proceedings of Space Utilization Symposium
The Twenty-sixth Space Utilization Symposium (January 25-26, 2010: ISAS/JAXA Sagamihara, Japan)
抄録（英）
Life on earth is constantly exposed to a variety of natural and artificial electromagnetic and static magnetic forces. In order to help clarify the effects of such exposure on biological systems, we investigate the effects of static magnetic fields on embryos of Xenopus laevis as well as the expression of Xotx2 (an important regulator of fore- and midbrain morphogenesis) and Xag1 (essential for cement gland formation). Results showed that: (1) Embryos developed from treated eggs were non-viable and had multiple malformations including two- or microcephalic heads, deformed cement glands and abnormal body proportions. The eyes and brain were morphological deficient or entirely absent. (2) Xotx2 and Xag1 expression was suppressed. Abnormal expression of these genes together with poor viability are possibly responsible for obstruction of egg cortex rotation, incomplete formation of grey crescent and changes in spatial distribution of genes.
両生類の生活環に対する強磁場の影響: 初期発生の形態学的および分子生物学的解析
64730085.pdf
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