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ベッドレスト前後でのヒト血清に含まれる変異調節活性の調査
https://jaxa.repo.nii.ac.jp/records/13807
https://jaxa.repo.nii.ac.jp/records/13807ce0ace33-77da-4c89-82d7-50265ccf87b7
Item type | 会議発表論文 / Conference Paper(1) | |||||
---|---|---|---|---|---|---|
公開日 | 2015-03-26 | |||||
タイトル | ||||||
タイトル | ベッドレスト前後でのヒト血清に含まれる変異調節活性の調査 | |||||
言語 | ||||||
言語 | jpn | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | ヒト血清 | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | ヘッドダウンチルト | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | ベッドレスト | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | 微小重力 | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | 培養ヒト細胞 | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | 突然変異 | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | パラボリックフライト | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | X線照射 | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | human serum | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | head down tilt | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | bed rest | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | microgravity | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | cultured human cell | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | mutation | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | parabolic flight | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | X-ray irradiation | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_5794 | |||||
資源タイプ | conference paper | |||||
アクセス権 | ||||||
アクセス権 | metadata only access | |||||
アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
その他のタイトル(英) | ||||||
その他のタイトル | Modulation of cell mutability by serum factors from volunteers who experienced head-down-tilt bed rest | |||||
著者 |
菅谷, 茂
× 菅谷, 茂× 喜多, 和子× 福岡, 秀興× 鈴木, 信夫× Sugaya, Shigeru× Kita, Kazuko× Fukuoka, Hideoki× Suzuki, Nobuo |
|||||
著者所属 | ||||||
千葉大学 大学院医学研究院 | ||||||
著者所属 | ||||||
千葉大学 大学院医学研究院 | ||||||
著者所属 | ||||||
東京大学 大学院医学系研究科 | ||||||
著者所属 | ||||||
千葉大学 大学院医学研究院 | ||||||
著者所属(英) | ||||||
en | ||||||
Chiba University Graduate School of Medicine | ||||||
著者所属(英) | ||||||
en | ||||||
Chiba University Graduate School of Medicine | ||||||
著者所属(英) | ||||||
en | ||||||
University of Tokyo Graduate School of Medicine | ||||||
著者所属(英) | ||||||
en | ||||||
Chiba University Graduate School of Medicine | ||||||
出版者 | ||||||
出版者 | 宇宙航空研究開発機構宇宙科学研究本部 | |||||
出版者(英) | ||||||
出版者 | Institute of Space and Astronautical Science, Japan Aerospace Exploration Agency (JAXA/ISAS) | |||||
書誌情報 |
宇宙利用シンポジウム 第20回 平成15年度 en : Space Utilization Research: Proceedings of the Twentieth Space Utilization Symposium p. 3-4, 発行日 2004-03 |
|||||
抄録(英) | ||||||
内容記述タイプ | Other | |||||
内容記述 | Head-down-tilt bed rest (BR) is utilized to mimic a microgravity environment. In this study, it was examined whether the modulating activity of serum factors on cell mutability was changed in seventeen volunteers subjected to BR. For comparison, serum was comparatively obtained from seven volunteers who experienced the parabolic flight (PF). Cultured human cells were treated with serum and then irradiated with UV or X-ray. Mutagenicity was estimated by identification of K-ras codon 12 base substitution mutation, following PCR and differential dot-blot hybridization. Modulating activity was detected in one sample from each of post-BR and post-PF serum. | |||||
資料番号 | ||||||
内容記述タイプ | Other | |||||
内容記述 | 資料番号: AA0046917002 |