Ochanomizu University Tateyama Marine Laboratory, Faculty of Science
Japan Aerospace Exploration Agency Institute of Space and Astronautical Science
University of Tokyo Research Center for Nuclear Science and Technology
出版者
宇宙航空研究開発機構宇宙科学研究本部
出版者（英）
Institute of Space and Astronautical Science, Japan Aerospace Exploration Agency (JAXA/ISAS)
雑誌名
宇宙利用シンポジウム 第20回 平成15年度
雑誌名(英)
Space Utilization Research: Proceedings of the Twentieth Space Utilization Symposium
ページ
26 - 28
発行年
2004-03
抄録（英）
Spicule formation by the cultured micromere of sea urchin was used as a model for the morphogenesis in biomineralization to be adapted as an experimental system in space. Several experiments were carried out in the different gravity environment to examine a role of gravity in the cells isolated from whole embryo and reported that spicule elongation was suppressed in the experiments of centrifugation, clinostat and the parabolic flight. The spicules of sea urchin larvae consist of calcite with magnesium and organic substances, called spicule matrix proteins. To examine the detail of the effect of these gravity conditions, RT-PCR was used to measure the level of expression of spicule matrix proteins in the cultured cells under each condition. The expression of one spicule matrix protein (SM30) was suppressed under the centrifugal condition. It also suppressed in the cells whose spicule elongation was suppressed in the culture on the ground after the parabolic flight. These results demonstrate that each gravity condition can effect on the gene expression of spicule matrix protein.
ウニ胚の骨片基質タンパク質の発現に対する重力環境の影響
