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クリノスタット培養の細胞内アクチンファイバー再構成への影響
https://jaxa.repo.nii.ac.jp/records/13816
https://jaxa.repo.nii.ac.jp/records/138164f714ef1-931a-417e-bcef-72e6aa049df5
Item type | 会議発表論文 / Conference Paper(1) | |||||
---|---|---|---|---|---|---|
公開日 | 2015-03-26 | |||||
タイトル | ||||||
タイトル | クリノスタット培養の細胞内アクチンファイバー再構成への影響 | |||||
言語 | ||||||
言語 | jpn | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | クリノローテーション | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | アクチンストレスファイバー | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | 蛍光顕微鏡 | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | 培養細胞 | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | タンパク質 | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | 遺伝子発現 | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | 活性化 | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | 重力効果 | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | clinorotation | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | actin stress fiber | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | fluorescent microscope | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | cultured cell | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | protein | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | gene expression | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | activation | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | gravitational effect | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_5794 | |||||
資源タイプ | conference paper | |||||
アクセス権 | ||||||
アクセス権 | metadata only access | |||||
アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
その他のタイトル(英) | ||||||
その他のタイトル | Effects of clinorotation on actin reformation in cells | |||||
著者 |
東端, 晃
× 東端, 晃× 関, 真也× 佐藤今溝, 真理× 石岡, 憲昭× Higashibata, Akira× Seki, Masaya× ImamizoSato, Mari× Ishioka, Noriaki |
|||||
著者所属 | ||||||
宇宙航空研究開発機構 宇宙科学研究本部 | ||||||
著者所属 | ||||||
エイ・イー・エス 宇宙開発部 | ||||||
著者所属 | ||||||
エイ・イー・エス 宇宙開発部 | ||||||
著者所属 | ||||||
宇宙航空研究開発機構 宇宙科学研究本部 | ||||||
著者所属(英) | ||||||
en | ||||||
Japan Aerospace Exploration Agency Institute of Space and Astronautical Science | ||||||
著者所属(英) | ||||||
en | ||||||
Advanced Engineering Services Co. Ltd. Space Development Division | ||||||
著者所属(英) | ||||||
en | ||||||
Advanced Engineering Services Co. Ltd. Space Development Division | ||||||
著者所属(英) | ||||||
en | ||||||
Japan Aerospace Exploration Agency Institute of Space and Astronautical Science | ||||||
出版者 | ||||||
出版者 | 宇宙航空研究開発機構宇宙科学研究本部 | |||||
出版者(英) | ||||||
出版者 | Institute of Space and Astronautical Science, Japan Aerospace Exploration Agency (JAXA/ISAS) | |||||
書誌情報 |
宇宙利用シンポジウム 第20回 平成15年度 en : Space Utilization Research: Proceedings of the Twentieth Space Utilization Symposium p. 29-30, 発行日 2004-03 |
|||||
抄録(英) | ||||||
内容記述タイプ | Other | |||||
内容記述 | Vector-altered gravity affects cytoskeletal formation. Actin stress fibers were disorganized under clinorotation, whereas the expression level of RhoA proteins, which stimulate the formation of actin stress fibers, was enhanced under that condition. From immunoblot analysis, the protein expression level of leukemia-associated Rho guanine nucleotide exchange factor (LARG), a kind of Rho-GEF, was depressed under clinorotation. And the gene expression level of LARG was also depressed under vector-averaged gravity. These results indicated that the depression of RhoA activation caused the disorganization of actin stress fiber, and Rho activation process might be affected by vector-averaged gravity. Signal transduction relating with Rho activation might be an important pathway of gravity sense and response mechanism on cells. | |||||
資料番号 | ||||||
内容記述タイプ | Other | |||||
内容記述 | 資料番号: AA0046917011 |