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アイテム
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宇宙放射線によるDNAクラスター損傷生成の可能性
https://jaxa.repo.nii.ac.jp/records/13911
https://jaxa.repo.nii.ac.jp/records/13911977f5c31-f3f1-42f3-b44a-3a43dce93c68
Item type | 会議発表論文 / Conference Paper(1) | |||||
---|---|---|---|---|---|---|
公開日 | 2015-03-26 | |||||
タイトル | ||||||
タイトル | 宇宙放射線によるDNAクラスター損傷生成の可能性 | |||||
言語 | ||||||
言語 | jpn | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | 宇宙放射線 | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | DNAクラスター損傷 | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | 鉄イオン | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | 重イオン加速器 | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | 生物効果 | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | 細胞 | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | 局所化 | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | LET | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | extraterrestrial radiation | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | DNA clustered damage | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | iron ion | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | heavy ion accelerator | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | biological effect | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | cell | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | localization | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | LET | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_5794 | |||||
資源タイプ | conference paper | |||||
アクセス権 | ||||||
アクセス権 | metadata only access | |||||
アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
その他のタイトル(英) | ||||||
その他のタイトル | A possible production of DNA clustered damage by space radiation | |||||
著者 |
冨田, 雅典
× 冨田, 雅典× 後藤, 佐智子× 谷田貝, 文夫× 松本, 義久× Tomita, Masanori× Goto, Sachiko× Yatagai, Fumio× Matsumoto, Yoshihisa |
|||||
著者所属 | ||||||
理化学研究所 ラジオアイソトープ技術室 | ||||||
著者所属 | ||||||
理化学研究所 ラジオアイソトープ技術室 | ||||||
著者所属 | ||||||
理化学研究所 ラジオアイソトープ技術室 | ||||||
著者所属 | ||||||
東京大学 大学院医学系研究科 | ||||||
著者所属(英) | ||||||
en | ||||||
Institute of Physical and Chemical Research Radioisotope Technology Division | ||||||
著者所属(英) | ||||||
en | ||||||
Institute of Physical and Chemical Research Radioisotope Technology Division | ||||||
著者所属(英) | ||||||
en | ||||||
Institute of Physical and Chemical Research Radioisotope Technology Division | ||||||
著者所属(英) | ||||||
en | ||||||
University of Tokyo Graduate School of Medicine | ||||||
出版者 | ||||||
出版者 | 宇宙科学研究所 | |||||
出版者(英) | ||||||
出版者 | The Institute of Space and Astronautical Science (ISAS) | |||||
書誌情報 |
宇宙利用シンポジウム 第19回 平成14年度 en : Space Utilization Research: Proceedings of the Nineteenth Space Utilization Symposium p. 9-11, 発行日 2003-02 |
|||||
抄録(英) | ||||||
内容記述タイプ | Other | |||||
内容記述 | Biological effect of heavy ions accelerated by ring cyclotron has been investigated, since heavy ions have been considered as predominantly important radiation to estimate biological effect by space radiation. Here it is reported that phosphorylated histone H2AX at ser 139 (gamma-H2AX) and NBS1, which are required for efficient DNA double-strand break repair by homologous recombination, form large undissolvable foci after exposure to accelerated Fe ions. These results suggest that unrepairable DNA clustered damage is induced by heavy ions, in vivo and gamma-H2AX and NBS1 can be used as molecular marker of DNA clustered damage. | |||||
資料番号 | ||||||
内容記述タイプ | Other | |||||
内容記述 | 資料番号: AA0045438004 |