CFD (Computational Fluid Dynamics) simulation associated with other analysis is necessary for the makers in order to keep flight and experiment safety. This paper shows several applications that were calculated so far in the company. First application is coupled with motion dynamics to simulate the separation from another body and the rotation of helicopter blades. Next one is done with the acoustics analysis to obtain the HSI (High Speed Impulsive) noise intensity. Last one is done with the structure analysis to capture the transformation of the space plane. CFD analysis associated with dynamic structure problems will be anticipated to be intensified as the collaborative work of the industries, government and universities.