WEKO3
アイテム
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魚類のウロコを用いた宇宙生物学的研究: 宇宙実験に適したウロコの培養法の検討
https://jaxa.repo.nii.ac.jp/records/13307
https://jaxa.repo.nii.ac.jp/records/133070ef452ca-63b7-48a4-a5d1-b4f66a2a8b11
名前 / ファイル | ライセンス | アクション |
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64297063.pdf (390.6 kB)
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Item type | 会議発表論文 / Conference Paper(1) | |||||
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公開日 | 2015-03-26 | |||||
タイトル | ||||||
タイトル | 魚類のウロコを用いた宇宙生物学的研究: 宇宙実験に適したウロコの培養法の検討 | |||||
言語 | ||||||
言語 | jpn | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | Fish scale; Osteoblasts; Osteoclasts; Regenerating scale; Culture; Hyper-gravity | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_5794 | |||||
資源タイプ | conference paper | |||||
その他のタイトル(英) | ||||||
その他のタイトル | Fish scale study for space biology: Application of scale culture method in the space environment | |||||
著者 |
鈴木, 信雄
× 鈴木, 信雄× 田畑, 純× 大森, 克徳× 井尻, 憲一× 北村, 敬一郎× 根本, 鉄× 清水, 宣明× 染井, 正徳× 池亀, 美華× 中村, 正久× Suzuki, Nobuo× Tabata, Makoto J.× Omori, Katsunori× Ijiri, Kenichi× Kitamura, Keiichiro× Nemoto, Tetsu× Shimizu, Nobuaki× Somei, Masanori× Ikegame, Mika× Nakamura, Masahisa |
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著者所属 | ||||||
金沢大学環日本海環境研究センター | ||||||
著者所属 | ||||||
東京医科歯科大学大学院 | ||||||
著者所属 | ||||||
宇宙航空研究開発機構 | ||||||
著者所属 | ||||||
東京大学アイソトープ総合センター | ||||||
著者所属 | ||||||
金沢大学大学院医学系研究科 | ||||||
著者所属 | ||||||
金沢大学大学院医学系研究科 | ||||||
著者所属 | ||||||
金沢大学環日本海環境研究センター | ||||||
著者所属 | ||||||
金沢大学大学院自然科学研究科 | ||||||
著者所属 | ||||||
岡山大学大学院医歯薬学総合研究科 | ||||||
著者所属 | ||||||
早稲田大学教育・総合科学学術院 | ||||||
著者所属(英) | ||||||
en | ||||||
Institute of Nature and Environmental Technology, Kanazawa University | ||||||
著者所属(英) | ||||||
en | ||||||
Graduate School, Tokyo Medical and Dental University | ||||||
著者所属(英) | ||||||
en | ||||||
Japan Aerospace Exploration Agency (JAXA) | ||||||
著者所属(英) | ||||||
en | ||||||
Radioisotope Center, University of Tokyo | ||||||
著者所属(英) | ||||||
en | ||||||
Graduate School of Medical Science, Kanazawa University | ||||||
著者所属(英) | ||||||
en | ||||||
Graduate School of Medical Science, Kanazawa University | ||||||
著者所属(英) | ||||||
en | ||||||
Institute of Nature and Environmental Technology, Kanazawa University | ||||||
著者所属(英) | ||||||
en | ||||||
Graduate School of Natural Science and Technology, Kanazawa University | ||||||
著者所属(英) | ||||||
en | ||||||
Graduate School of Medicine, Dentistry and Pharmaceutical Science, Okayama University | ||||||
著者所属(英) | ||||||
en | ||||||
Faculty of Education and Integrated Arts and Sciences, Waseda University | ||||||
出版者 | ||||||
出版者 | 宇宙航空研究開発機構宇宙科学研究本部 | |||||
出版者(英) | ||||||
出版者 | Institute of Space and Astronautical Science, Japan Aerospace Exploration Agency (JAXA) | |||||
書誌情報 |
宇宙利用シンポジウム en : Space Utilization Research: Proceedings of Space Utilization Symposium 巻 25, 発行日 2009-03 |
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会議概要(会議名, 開催地, 会期, 主催者等) | ||||||
内容記述タイプ | Other | |||||
内容記述 | 第25回宇宙利用シンポジウム(2009年1月14日-15日, 宇宙航空研究開発機構宇宙科学研究本部相模原キャンパス) | |||||
会議概要(会議名, 開催地, 会期, 主催者等)(英) | ||||||
内容記述タイプ | Other | |||||
内容記述 | The Twenty-fifth Space Utilization Symposium (January 14-15, 2009: ISAS/JAXA Sagamihara, Japan) | |||||
抄録(英) | ||||||
内容記述タイプ | Other | |||||
内容記述 | Fish scale is a calcified tissue that contains osteoblasts, osteoclasts, and bone matrix, all of which are similar to those found in mammalian membrane bone. Recently, we developed a new in vitro model system using goldfish scales. This system can detect the activities of osteoblasts and osteoclasts with alkaline phosphatase (ALP) and tartrate-resistant acid phosphatase (TRAP) as respective markers and can analyze the co-relationship between osteoblasts and osteoclasts. Using this system, we previously indicated that osteoblastic and osteoclastic activities in the scales responded to simulated microgravity with a three-dimensional clinostat. As these activities in the scales were not changed by stimulation with a two-dimensional clinostat, we believe that the response to simulated microgravity in scale osteoblasts and osteoclasts is a specific phenomenon. Thus, to analyze bone metabolism in scales under microgravity conditions such as those experienced during space flights, we examined culture conditions in goldfish scales. We found that normal scales and regenerating scales treated by hypochlorous acid could be cultured in Leibovitz L-15 medium supplemented with 10 % fetal bovine serum for 1 week at 25 C. After these scales were kept in the above medium at 4 C, the response of hyper-gravity loading under acceleration by vibration (3 G, 10 min) was examined. The TRAP activities in the normal and regenerating scales kept at 4 C for 1 week significantly decreased, while ALP activities in these scales significantly increased. These responses in the scales kept at 4 C for 1 week were very similar to those in the untreated scales just after collection from goldfish. We concluded that fish scales are a suitable material for the analysis of bone metabolism under microgravity conditions, such as those experienced during space flights. | |||||
内容記述 | ||||||
内容記述タイプ | Other | |||||
内容記述 | 著者人数: 25人 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AN10324210 | |||||
資料番号 | ||||||
内容記述タイプ | Other | |||||
内容記述 | 資料番号: AA0064297063 |