@inproceedings{oai:jaxa.repo.nii.ac.jp:00013100, author = {野村, 大成 and 梁, 治子 and 足立, 成基 and 時田, 偉子 and 堀家, なな緒 and 畑中, 英子 and 菊谷, 理絵 and 中島, 裕夫 and 本行, 忠志 and 藤川, 和男 and Nomura, Taisei and Ryo, Haruko and Adachi, Shigeki and Tokita, Yoriko and Horike, Nanao and Hatanaka, Eiko and Kikuya, Rie and Nakajima, Hiroo and Hongyo, Tadashi and Fujikawa, Kazuo}, book = {宇宙利用シンポジウム: 第27回: 平成22年度, Space Utilization Research, Vol. 27 2011: Proceedings of The Twenty-seventh Space Utilization Symposium}, month = {Mar}, note = {第27回宇宙利用シンポジウム (2011年1月24日-25日, 宇宙航空研究開発機構宇宙科学研究所相模原キャンパス), 相模原市, 神奈川県, The Twenty-seventh Space Utilization Symposium (January 24-25, 2011. Institute of Space and Astronautical Science, Japan Aerospace Exploration Agency (JAXA)(ISAS)), Sagamihara, Kanagawa Japan, To study the human risk of cosmic environment (including neutrons) in the flying body and space base, (1) Morphological and functional effects (including changes in gene expression) of fission neutrons on human thyroid tissues maintained in super-SCID (severe combined immunodeficient) mice, (2) Microsatellite mutations and leukemia in the offspring of mice in the space environment, and (3) Protection of radiation-induced defects by food and supplement, and effects of space environment (including micro-gravity) on human diseases are carried out by using specific mouse models. The first two projects are ready to be carried out in the space environment, although these were cancelled in Japan (and also in USA and EU). As for Project 3, we demonstrated protection of leukemia and congenital anomalies by AHCC (Active Hexose Correlated Compound) treatment, and strong effects of micro-gravity (microG) on behavior and gene expression by parabolic flight were shown with panic mouse model., 著者人数: 14人, 形態: カラー図版あり, Number of authors: 14, Physical characteristics: Original contains color illustrations, 資料番号: AA0065129040}, pages = {107--110}, publisher = {宇宙航空研究開発機構宇宙科学研究所 (JAXA)(ISAS), Institute of Space and Astronautical Science, Japan Aerospace Exploration Agency (JAXA)(ISAS)}, title = {宇宙環境の人体影響評価と防護に関する研究}, volume = {27}, year = {2011} }