@inproceedings{oai:jaxa.repo.nii.ac.jp:00013139,
 author = {鈴木, 信雄 and 大森, 克徳 and 井尻, 憲一 and 北村, 敬一郎 and 根本, 鉄 and 清水, 宣明 and 笹山, 雄一 and 西内, 巧 and 染井, 正徳 and 池亀, 美華 and 田畑, 純 and 中村, 正久 and 近藤, 隆 and 古澤, 之裕 and 松田, 恒平 and 田淵, 圭章 and 高橋, 一朗 and 和田, 重人 and 安東, 宏徳 and 笠原, 春夫 and 永瀬, 睦 and 久保田, 幸治 and 土屋, 美和 and 谷川, 直樹 and 吉馴, 重徳 and 大嶋, 一成 and 鈴木, 徹 and 遠藤, 雅人 and 竹内, 俊郎 and 江尻, 貞一 and 小萱, 康徳 and 前田, 斉嘉 and 内田, 秀明 and 田谷, 敏貴 and 林, 明生 and 中村, 貞夫 and 杉立, 久仁代 and 芹野, 武 and 嶋津, 徹 and 矢野, 幸子 and Suzuki, Nobuo and Omori, Katsunori and Ijiri, Kenichi and Kitamura, Keiichiro and Nemoto, Tetsu and Shimizu, Nobuaki and Sasayama, Yuichi and Nishiuchi, Takumi and Somei, Masanori and Ikegame, Mika and Tabata, Makoto J. and Nakamura, Masahisa and Kondo, Takashi and Furusawa, Yukihiro and Matsuda, Kohei and Tabuchi, Yoshiaki and Takahashi, Ichiro and Wada, Shigehito and Ando, Hironori and Kasahara, Haruo and Nagase, Mutsumu and Kubota, Koji and Tsuchiya, Yoshikazu and Tanigawa, Naoki and Yoshinari, Shigenori and Oshima, Kazunari and Suzuki, Toru and Endo, Masato and Takeuchi, Toshio and Ejiri, Sadakazu and Kogaya, Yasutoku and Maeda, Masahiro and Uchida, Hideaki and Taya, Toshiki and Hayashi, Akio and Nakamura, Sadao and Sugitate, Kuniyo and Serino, Takeshi and Shimazu, Toru and Yano, Sachiko},
 book = {宇宙利用シンポジウム: 第27回: 平成22年度, Space Utilization Research, Vol. 27 2011: Proceedings of The Twenty-seventh Space Utilization Symposium},
 month = {Mar},
 note = {第27回宇宙利用シンポジウム (2011年1月24日-25日, 宇宙航空研究開発機構宇宙科学研究所相模原キャンパス), 相模原市, 神奈川県, The Twenty-seventh Space Utilization Symposium (January 24-25, 2011. Institute of Space and Astronautical Science, Japan Aerospace Exploration Agency (JAXA)(ISAS)), Sagamihara, Kanagawa Japan, Fish scale is calcified tissue that contains osteoblasts, osteoclasts, and the bone matrix, all of which are similar to those found in mammalian membrane bone. Recently, we developed a new in vitro assay system using fish scale, which can be used to detect the activities of scale osteoblasts and osteoclasts simultaneously using the alkaline phosphatase (ALP) and the tartrate-resistant acid phosphatase (TRAP) assay, respectively. Using the assay system, we examined hyper-gravity (3G) responses by centrifuge and vibration in the fish scales and compared these responses with those in the mouse calvarial bone. In addition, we developed an apparatus for space experiments using a recovery satellite and examined hyper-gravity (3G) by vibration responses to the fish scales. We found that the ALP activity in the goldfish scales significantly increased under 3G loading by centrifuge and vibration, while the TRAP activity in both loaded scales of goldfish significantly decreased. Similar results were obtained in the mouse calvarial bone. The goldfish scales that were put into the bag that would be used in the recovery satellite responded to hyper-gravity responses by vibration, as explained above. Thus, our assay system may help explain the mechanism of bone loss, such as that occurring during space flight., 著者人数: 42人, 形態: カラー図版あり, Number of authors: 42, Physical characteristics: Original contains color illustrations, 資料番号: AA0065129079},
 pages = {209--212},
 publisher = {宇宙航空研究開発機構宇宙科学研究所 (JAXA)(ISAS), Institute of Space and Astronautical Science, Japan Aerospace Exploration Agency (JAXA)(ISAS)},
 title = {魚類のウロコを用いた宇宙生物学的研究: ウロコ及びマウスの頭蓋骨に対する重力応答},
 volume = {27},
 year = {2011}
}