@inproceedings{oai:jaxa.repo.nii.ac.jp:00013140, author = {矢野, 幸子 and Aizawa-Yano, Sachiko}, book = {宇宙利用シンポジウム: 第27回: 平成22年度, Space Utilization Research, Vol. 27 2011: Proceedings of The Twenty-seventh Space Utilization Symposium}, month = {Mar}, note = {第27回宇宙利用シンポジウム (2011年1月24日-25日, 宇宙航空研究開発機構宇宙科学研究所相模原キャンパス), 相模原市, 神奈川県, The Twenty-seventh Space Utilization Symposium (January 24-25, 2011. Institute of Space and Astronautical Science, Japan Aerospace Exploration Agency (JAXA)(ISAS)), Sagamihara, Kanagawa Japan, In space flight, bone resorption by osteoclasts has been observed inconsistently until now. The Japan Aerospace Exploration Agency (JAXA) carried out the Fish Scales experiment using the Measurement Experiment Unit (MEU) installed in the Cell Biology Experiment Facility (CBEF) on board Kibo. This experiment was designed to investigate the effect of microgravity on goldfish scales. Space shuttle STS-132 (ULF4), which carried the specimens, was launched to the International Space Station (ISS) on May 14, 2010. The experiment was started on May 16 and terminated on May 20, 2010. The MEU and CBEF environment control systems worked as planned. On May 26, 2010, the specimens cultured in Kibo were returned to Earth by space shuttle STS-132 and analyzed for their biological characteristics. In the Fish Scales experiment, a biological experiment including in vitro cell culture, temperature control was a key factor in the success of the experiment. In this report, experimental data regarding culture temperature in the CBEF and other temperature-maintaining systems during transportation between the ground and ISS are described, as well as the onboard operations by the ISS crew member. Judging by temperature data in the hardware under microgravity and in ground conditions, our experiment seems to have succeeded. The Fish Scales research team will analyze the cell activity, the osteoblastic and osteoclastic marker mRNA expression, and the cell morphology in the goldfish scales kept in microgravity. The results will be compared with ground controls and onboard 1G control scales to determine the effect of space on bone metabolism., 形態: カラー図版あり, Physical characteristics: Original contains color illustrations, 資料番号: AA0065129080}, pages = {213--216}, publisher = {宇宙航空研究開発機構宇宙科学研究所 (JAXA)(ISAS), Institute of Space and Astronautical Science, Japan Aerospace Exploration Agency (JAXA)(ISAS)}, title = {Preparation and Overview of Fish Scales Experiment}, volume = {27}, year = {2011} }