@inproceedings{oai:jaxa.repo.nii.ac.jp:00013192, author = {西村, 直記 and 岩瀬, 敏 and 塩澤, 友規 and 菅屋, 潤壹 and 清水, 祐樹 and 高田, 真澄 and 犬飼, 洋子 and 佐藤, 麻紀 and 鈴木, 里美 and 石田, 浩司 and 秋間, 広 and 片山, 敬章 and 増尾, 善久 and 間野, 忠明 and Nishimura, Naoki and Iwase, Satoshi and Shiozawa, Tomoki and Sugenoya, Junichi and Shimizu, Yuuki and Takada, Masumi and Inukai, Yoko and Sato, Maki and Kanikowska, Dominika and Suzuki, Satomi and Ishida, Koji and Akima, Hiroshi and Katayama, Keisho and Masuo, Yoshihisa and Mano, Tadaaki}, book = {宇宙利用シンポジウム, Space Utilization Research: Proceedings of Space Utilization Symposium}, month = {Feb}, note = {第26回宇宙利用シンポジウム(2010年1月25日-26日, 宇宙航空研究開発機構宇宙科学研究本部相模原キャンパス), The Twenty-sixth Space Utilization Symposium (January 25-26, 2010: ISAS/JAXA Sagamihara, Japan), We investigated that artificial gravity and ergometric exercise as the countermeasure throughout -6 deg head-down bed rest (HDBR) for 20 days prevent bone metabolic deconditioning. Twelve healthy male subjects participated in this study. During the HDBR, 6 subjects performed ergometric exercise with artificial gravity for cumulative 30 min per day (countermeasure group), while 6 subjects underwent the same HDBR procedure without countermeasure (control group). In countermeasure group, urinary deoxypiridinorine (DPD) and crosslinked N-telopeptides of type I collagen (NTX) as an index of osteoclast activity were not significant difference between before and after HDBR, whereas it increased after HDBR in the control group. In control group, the increase of DPD was linearly related to the muscle sympathetic nerve activity. In conclusion, bone metabolic deconditioning after HDBR was prevented by countermeasure of everyday, and sympathetic nerve activity might be related to bone metabolism., 共催: 日本学術会議, 著者人数: 15人, joint hosting: The Science Council of Japan, 資料番号: AA0064730045}, publisher = {宇宙航空研究開発機構宇宙科学研究本部, Institute of Space and Astronautical Science, Japan Aerospace Exploration Agency (JAXA)}, title = {模擬微小重力曝露後の骨代謝デコンディショニングに対する対抗措置の有効性}, volume = {26}, year = {2010} }