@inproceedings{oai:jaxa.repo.nii.ac.jp:00013198,
 author = {森田, 啓之 and 安部, 力 and 川田, 徹 and 田中, 邦彦 and 杉町, 勝 and Morita, Hironobu and Abe, Chikara and Kawada, Toru and Tanaka, Kunihiko and Sugimachi, Masaru},
 book = {宇宙利用シンポジウム, Space Utilization Research: Proceedings of Space Utilization Symposium},
 month = {Feb},
 note = {第26回宇宙利用シンポジウム(2010年1月25日-26日, 宇宙航空研究開発機構宇宙科学研究本部相模原キャンパス), The Twenty-sixth Space Utilization Symposium (January 25-26, 2010: ISAS/JAXA Sagamihara, Japan), Head-up tilt (HUT) elicits gravitational fluid shift and a decrease in arterial pressure (AP), which is thought to be buffered by baroreflex and vestibulo-sympathetic reflex. However, functional interaction between these reflexes has not been clear. To examine this, renal sympathetic nerve activity (SNA) and AP were measured in anesthetized, vagotomized, and aortic denervated rats with or without vestibular lesion (VL). Isolated carotid sinus pressure (CSP) was increased stepwise from 60 to 180 mmHg with increments of 20 mmHg (30-60 s for each CSP level) while the rat was placed prone flat position and at 60 deg HUT. HUT shifted the CSP-SNA relationship (the baroreflex central arc) to a higher SNA, shifted the SNA-AP relationship (the baroreflex peripheral arc) to a lower AP, and consequently moved the operating point to high SNA while maintaining AP. In VL rats, the HUT-induced central arc shift was completely abolished, while the peripheral arc shifted to a lower AP; the operating point moved to a lower AP (-25 mmHg). These results indicate that the vestibular system elicits sympathoexcitation upon HUT and shifts the baroreflex central arc to a higher SNA and then maintain baroreflex operating AP., 共催: 日本学術会議, joint hosting: The Science Council of Japan, 資料番号: AA0064730051},
 publisher = {宇宙航空研究開発機構宇宙科学研究本部, Institute of Space and Astronautical Science, Japan Aerospace Exploration Agency (JAXA)},
 title = {姿勢変換時の血圧維持における圧受容器と前庭系の関与},
 volume = {26},
 year = {2010}
}