{"created":"2023-06-20T14:45:44.761344+00:00","id":13224,"links":{},"metadata":{"_buckets":{"deposit":"d3a84cba-4c66-497b-b0c7-12e789996bc8"},"_deposit":{"created_by":1,"id":"13224","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"13224"},"status":"published"},"_oai":{"id":"oai:jaxa.repo.nii.ac.jp:00013224","sets":["1543:1633:1641","1887:1891"]},"author_link":["119423","119409","119412","119416","119426","119413","119422","119419","119417","119415","119410","119421","119408","119407","119414","119418","119424","119420","119411","119425"],"item_5_alternative_title_2":{"attribute_name":"その他のタイトル（英）","attribute_value_mlt":[{"subitem_alternative_title":"Fish Scale Study for Space Biology: Hormonal Responses in the Fish Scale"}]},"item_5_biblio_info_10":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2010-02","bibliographicIssueDateType":"Issued"},"bibliographicVolumeNumber":"26","bibliographic_titles":[{"bibliographic_title":"宇宙利用シンポジウム"},{"bibliographic_title":"Space Utilization Research: Proceedings of Space Utilization Symposium","bibliographic_titleLang":"en"}]}]},"item_5_description_14":{"attribute_name":"会議概要（会議名, 開催地, 会期, 主催者等）","attribute_value_mlt":[{"subitem_description":"第26回宇宙利用シンポジウム(2010年1月25日-26日, 宇宙航空研究開発機構宇宙科学研究本部相模原キャンパス)","subitem_description_type":"Other"}]},"item_5_description_15":{"attribute_name":"会議概要（会議名, 開催地, 会期, 主催者等）（英）","attribute_value_mlt":[{"subitem_description":"The Twenty-sixth Space Utilization Symposium (January 25-26, 2010: ISAS/JAXA Sagamihara, Japan)","subitem_description_type":"Other"}]},"item_5_description_17":{"attribute_name":"抄録（英）","attribute_value_mlt":[{"subitem_description":"Fish scale is a calcified tissue that contains osteoblasts, osteoclasts, and the bone matrix of two layers (a bony layer: a thin, well-calcified external layer; and a fibrillary layer: a thick, partially calcified layer), all of which are similar to those found in mammalian membrane bone. Recently, we developed a new in vitro model system using goldfish scales. This system can be used to detect the activities of osteoblasts and osteoclasts with alkaline phosphatase (ALP) and tartrate-resistant acid phosphatase (TRAP) as respective markers. Therefore, it can be used to analyze the co-relationship between osteoblasts and osteoclasts. To obtain basic data for a space experiment, effects of calcemic hormones, such as parathyroid hormone (PTH), calcitonin, vitamin D3, and insulin-like growth factor-I on osteoblasts and osteoclasts in the scale, were examined using this assay in the present study. PTH activated osteoblastic activity and then increased osteoclastic activity. Furthermore, we found that other calcemic hormones function in both osteoclasts and osteoblasts in the fish scale as they do in mammals. Thus, scale is a functional calcium reservoir and has a physiological significance role in the bone metabolism of teleosts. Our assay system may help explain the mechanism of bone loss, such as that occurring during space flight.","subitem_description_type":"Other"}]},"item_5_description_18":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"共催: 日本学術会議","subitem_description_type":"Other"},{"subitem_description":"著者人数: 35人","subitem_description_type":"Other"}]},"item_5_description_19":{"attribute_name":"内容記述（英）","attribute_value_mlt":[{"subitem_description":"joint hosting: The Science Council of Japan","subitem_description_type":"Other"}]},"item_5_description_32":{"attribute_name":"資料番号","attribute_value_mlt":[{"subitem_description":"資料番号: AA0064730077","subitem_description_type":"Other"}]},"item_5_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"宇宙航空研究開発機構宇宙科学研究本部"}]},"item_5_publisher_9":{"attribute_name":"出版者（英）","attribute_value_mlt":[{"subitem_publisher":"Institute of Space and Astronautical Science, Japan Aerospace Exploration Agency (JAXA)"}]},"item_5_source_id_24":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AN10324210","subitem_source_identifier_type":"NCID"}]},"item_5_text_6":{"attribute_name":"著者所属","attribute_value_mlt":[{"subitem_text_value":"金沢大学環日本海環境研究センター"},{"subitem_text_value":"東京医科歯科大学大学院"},{"subitem_text_value":"宇宙航空研究開発機構宇宙科学研究本部ISS科学プロジェクト室"},{"subitem_text_value":"東京大学アイソトープ総合センター"},{"subitem_text_value":"金沢大学大学院医学系研究科"},{"subitem_text_value":"金沢大学大学院医学系研究科"},{"subitem_text_value":"金沢大学環日本海環境研究センター"},{"subitem_text_value":"金沢大学環日本海環境研究センター"},{"subitem_text_value":"金沢大学大学院自然科学研究科"},{"subitem_text_value":"岡山大学大学院医歯薬学総合研究科"}]},"item_5_text_7":{"attribute_name":"著者所属（英）","attribute_value_mlt":[{"subitem_text_language":"en","subitem_text_value":"Institute of Nature and Environmental Technology, Kanazawa University"},{"subitem_text_language":"en","subitem_text_value":"Graduate School, Tokyo Medical and Dental University"},{"subitem_text_language":"en","subitem_text_value":"ISS Science Project Office, Institute of Space and Astronautical Science, Japan Aerospace Exploration Agency (JAXA)(ISAS)"},{"subitem_text_language":"en","subitem_text_value":"Radioisotope Center, University of Tokyo"},{"subitem_text_language":"en","subitem_text_value":"Graduate School of Medical Science, Kanazawa University"},{"subitem_text_language":"en","subitem_text_value":"Graduate School of Medical Science, Kanazawa University"},{"subitem_text_language":"en","subitem_text_value":"Institute of Nature and Environmental Technology, Kanazawa University"},{"subitem_text_language":"en","subitem_text_value":"Institute of Nature and Environmental Technology, Kanazawa University"},{"subitem_text_language":"en","subitem_text_value":"Graduate School of Natural Science and Technology, Kanazawa University"},{"subitem_text_language":"en","subitem_text_value":"Graduate School of Medicine, Dentistry and Pharmaceutical Science, Okayama University"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"鈴木, 信雄"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"田畑, 純"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"大森, 克徳"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"井尻, 憲一"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"北村, 敬一郎"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"根本, 鉄"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"清水, 宣明"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"笹山, 雄一"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"染井, 正徳"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"池亀, 美華"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Suzuki, Nobuo","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Tabata, Makoto J.","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Omori, Katsunori","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Ijiri, Kenichi","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Kitamura, Keiichiro","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Nemoto, Tetsu","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Shimizu, Nobuaki","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Sasayama, Yuichi","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Somei, Masanori","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Ikegame, Mika","creatorNameLang":"en"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-01-20"}],"displaytype":"detail","filename":"64730077.pdf","filesize":[{"value":"514.8 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"64730077.pdf","url":"https://jaxa.repo.nii.ac.jp/record/13224/files/64730077.pdf"},"version_id":"6bfc0eaa-389e-4dc3-8df2-39212fc7be04"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Fish scale; Osteoblasts; Osteoclasts; Calcemic hormones","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"conference 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