@inproceedings{oai:jaxa.repo.nii.ac.jp:00013225,
 author = {堀, 友香 and 向井, 千夏 and 奥野, 誠 and Hori, Tomoka and Mukai, Chinatsu and Okuno, Makoto},
 book = {宇宙利用シンポジウム, Space Utilization Research: Proceedings of Space Utilization Symposium},
 month = {Feb},
 note = {第26回宇宙利用シンポジウム(2010年1月25日-26日, 宇宙航空研究開発機構宇宙科学研究本部相模原キャンパス), The Twenty-sixth Space Utilization Symposium (January 25-26, 2010: ISAS/JAXA Sagamihara, Japan), We demonstrated previously that the growth rate was suppressed by exposure to hyper gravity, 3G, in young (3-5 weeks old) male mouse in which the mouse seemed to be in repletion. In the present experiment, the effects of hyper gravity on appestat were examined using mature male mouse (7 weeks old or more) in order to eliminate the factors relating growth. Since the stress hormone (corticosterone) level increased on day 2 but was restored down to the normal level on day 4 and 8 we examined the effects of 3G on the appestat hormones on day 2 and day 8. Leptin and insulin decreased and ghrelin incresed by 3G exposure, suggesting that the mouse was starving hungry in blood hormone level. These results should have to lead increase of NPY (neuropeptide Y) at hypothalamus usually. However, immunofluorescent observation revealed that the expression of NPY decreased resulting in repletion in behavior level. Therefore, it is likely that hyper gravity causes some effects on NPY neurons., 形態: カラー図版あり, 共催: 日本学術会議, Physical characteristics: Original contains color illustrations, joint hosting: The Science Council of Japan, 資料番号: AA0064730078},
 publisher = {宇宙航空研究開発機構宇宙科学研究本部, Institute of Space and Astronautical Science, Japan Aerospace Exploration Agency (JAXA)},
 title = {マウスの食欲調節機構に対する過重力の影響},
 volume = {26},
 year = {2010}
}