@inproceedings{oai:jaxa.repo.nii.ac.jp:00013232, author = {柏木, 啓子 and 藤原, 好恒 and 坂尾, 智美 and 古野, 伸明 and 柳澤, 誠 and 花田, 秀樹 and 谷本, 能文 and 山下, 雅道 and 渡部, 稔 and 新海, 正 and Kashiwagi, Keiko and Fujiwara, Yoshihisa and Sakao, Satomi and Furuno, Nobuaki and Yanagisawa, Makoto and Hanada, Hideki and Tanimoto, Yoshifumi and Yamashita, Masamichi and Watanabe, Minoru and Shinkai, Tadashi}, book = {宇宙利用シンポジウム, Space Utilization Research: Proceedings of Space Utilization Symposium}, month = {Feb}, note = {第26回宇宙利用シンポジウム(2010年1月25日-26日, 宇宙航空研究開発機構宇宙科学研究本部相模原キャンパス), The Twenty-sixth Space Utilization Symposium (January 25-26, 2010: ISAS/JAXA Sagamihara, Japan), Life on earth is constantly exposed to a variety of natural and artificial electromagnetic and static magnetic forces. In order to help clarify the effects of such exposure on biological systems, we investigate the effects of static magnetic fields on embryos of Xenopus laevis as well as the expression of Xotx2 (an important regulator of fore- and midbrain morphogenesis) and Xag1 (essential for cement gland formation). Results showed that: (1) Embryos developed from treated eggs were non-viable and had multiple malformations including two- or microcephalic heads, deformed cement glands and abnormal body proportions. The eyes and brain were morphological deficient or entirely absent. (2) Xotx2 and Xag1 expression was suppressed. Abnormal expression of these genes together with poor viability are possibly responsible for obstruction of egg cortex rotation, incomplete formation of grey crescent and changes in spatial distribution of genes., 共催: 日本学術会議, 著者人数: 17人, joint hosting: The Science Council of Japan, 資料番号: AA0064730085}, publisher = {宇宙航空研究開発機構宇宙科学研究本部, Institute of Space and Astronautical Science, Japan Aerospace Exploration Agency (JAXA)}, title = {両生類の生活環に対する強磁場の影響: 初期発生の形態学的および分子生物学的解析}, volume = {26}, year = {2010} }