@inproceedings{oai:jaxa.repo.nii.ac.jp:00013236, author = {大森, 克徳 and 石岡, 憲昭 and 鈴木, ひろみ and 嶋津, 徹 and 関, 真也 and 橋爪, 藤子 and 高橋, 昭久 and 大西, 武雄 and 谷田貝, 文夫 and Omori, Katsunori and Ishioka, Noriaki and Suzuki, Hiromi and Shimazu, Toru and Seki, Masaya and Hashizume, Toko and Takahashi, Akihisa and Onishi, Takeo and Yatagai, Fumio}, book = {宇宙利用シンポジウム, Space Utilization Research: Proceedings of Space Utilization Symposium}, month = {Feb}, note = {第26回宇宙利用シンポジウム(2010年1月25日-26日, 宇宙航空研究開発機構宇宙科学研究本部相模原キャンパス), The Twenty-sixth Space Utilization Symposium (January 25-26, 2010: ISAS/JAXA Sagamihara, Japan), To study about space radiation effects on human cultured cells, two flight experiments of Rad Gene and LOH have been scheduled since about 8-10 years ago. As the first life-experiment in ISS, they were performed. A space shuttle "Endeavor" was launched from KSC on Nov. 15th, 2008 (STS-126) and arrived to earth by "Discovery" on Mar. 29th, 2009(STS-119). Total flight was 133 days 19hrs 42 min. We prepared two cell lines of human culture cells bearing different p53 gene status for culture in a Cell Biology Experiment Facility (CBEF), for frozen condition in a Minus Eighty degree Celsius Laboratory Freezer in ISS (MELFI) and for the ground control. CBEF has two areas of micro- and 1g-facilities. We can compare the effect of microgravity on biological phenomenon such as gene expression, chromosomal aberration and mutation and so on by using two areas in CBEF with or without gravity. On the other hand, we can compare the space radiation effects on them from the comparison of flight experiments with 1g and the ground control experiments. Flight experiments started Feb. 20th, 2009 and finished 28th for 8 days. Crew training was done on July 9th, 2008 at JAXA, Tsukuba. In these experiments, many schedules were changed from the reason of the delay of shuttle flight. However, whole scheduled experiments were successful. Today, next speakers will show the interesting and exciting data surely., 形態: カラー図版あり, 共催: 日本学術会議, Physical characteristics: Original contains color illustrations, joint hosting: The Science Council of Japan, 資料番号: AA0064730089}, publisher = {宇宙航空研究開発機構宇宙科学研究本部, Institute of Space and Astronautical Science, Japan Aerospace Exploration Agency (JAXA)}, title = {「きぼう」でのRad Gene/LOH宇宙実験報告: 提案, 準備, 宇宙実験運用}, volume = {26}, year = {2010} }