{"created":"2023-06-20T14:45:47.330290+00:00","id":13282,"links":{},"metadata":{"_buckets":{"deposit":"9305f53c-0d28-4daa-a48e-b23c8755dcab"},"_deposit":{"created_by":1,"id":"13282","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"13282"},"status":"published"},"_oai":{"id":"oai:jaxa.repo.nii.ac.jp:00013282","sets":["1543:1633:1642","1887:1891"]},"author_link":["120314","120313","120312","120309","120315","120310","120308","120311"],"item_5_alternative_title_2":{"attribute_name":"その他のタイトル（英）","attribute_value_mlt":[{"subitem_alternative_title":"Effectiveness of bone marrow stromal cell cultured under microgravity in neurogenesis"}]},"item_5_biblio_info_10":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2009-03","bibliographicIssueDateType":"Issued"},"bibliographicVolumeNumber":"25","bibliographic_titles":[{"bibliographic_title":"宇宙利用シンポジウム"},{"bibliographic_title":"Space Utilization Research: Proceedings of Space Utilization Symposium","bibliographic_titleLang":"en"}]}]},"item_5_description_14":{"attribute_name":"会議概要（会議名, 開催地, 会期, 主催者等）","attribute_value_mlt":[{"subitem_description":"第25回宇宙利用シンポジウム(2009年1月14日-15日, 宇宙航空研究開発機構宇宙科学研究本部相模原キャンパス)","subitem_description_type":"Other"}]},"item_5_description_15":{"attribute_name":"会議概要（会議名, 開催地, 会期, 主催者等）（英）","attribute_value_mlt":[{"subitem_description":"The Twenty-fifth Space Utilization Symposium (January 14-15, 2009: ISAS/JAXA Sagamihara, Japan)","subitem_description_type":"Other"}]},"item_5_description_17":{"attribute_name":"抄録（英）","attribute_value_mlt":[{"subitem_description":"Recently, regenerative medicine with bone marrow stromal cells (BMSCs) has gained significant attention for the treatment of central nervous system diseases. Here, we investigated the activity of BMSCs under simulated microgravity conditions, with special focus on their cellular responses to physical stimulation. In conclusion, we demonstrated that mouse BMSCs maintained multipotency in culture in 3D-clinostat, and their transplantation may contribute to recovery of functions in injured brain. Establishing cell therapy needs a mean of maintaining multipotency in donor cells for future use. This study suggests that simulated microgravity could be a candidate for that.","subitem_description_type":"Other"}]},"item_5_description_32":{"attribute_name":"資料番号","attribute_value_mlt":[{"subitem_description":"資料番号: AA0064297038","subitem_description_type":"Other"}]},"item_5_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"宇宙航空研究開発機構宇宙科学研究本部"}]},"item_5_publisher_9":{"attribute_name":"出版者（英）","attribute_value_mlt":[{"subitem_publisher":"Institute of Space and Astronautical Science, Japan Aerospace Exploration Agency (JAXA)"}]},"item_5_source_id_24":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AN10324210","subitem_source_identifier_type":"NCID"}]},"item_5_text_6":{"attribute_name":"著者所属","attribute_value_mlt":[{"subitem_text_value":"広島大学"},{"subitem_text_value":"広島大学"},{"subitem_text_value":"広島大学"},{"subitem_text_value":"テキサス大学"},{"subitem_text_value":"ジョンホプキンス大学"}]},"item_5_text_7":{"attribute_name":"著者所属（英）","attribute_value_mlt":[{"subitem_text_language":"en","subitem_text_value":"Hiroshima University"},{"subitem_text_language":"en","subitem_text_value":"Hiroshima University"},{"subitem_text_language":"en","subitem_text_value":"Hiroshima University"},{"subitem_text_language":"en","subitem_text_value":"Medical School, University of Texas"},{"subitem_text_language":"en","subitem_text_value":"School of Medicine, Johns Hopkins University"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"弓削, 類"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"田原, 栄俊"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"河原, 裕美"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Yuge, Louis","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Tahara, Hidetoshi","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Kawahara, Yumi","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Kulkarni, Anil D.","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Romer, Lewis","creatorNameLang":"en"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-01-20"}],"displaytype":"detail","filename":"64297038.pdf","filesize":[{"value":"10.4 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"64297038.pdf","url":"https://jaxa.repo.nii.ac.jp/record/13282/files/64297038.pdf"},"version_id":"e80af208-fa77-46c7-9d93-593abbb86a4f"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Simulated Microgravity, Neurogenesis, Bone Marrow Stromal Cells","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"conference paper","resourceuri":"http://purl.org/coar/resource_type/c_5794"}]},"item_title":"神経再生における微小重力環境で培養した骨髄間質系細胞の有用性","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"神経再生における微小重力環境で培養した骨髄間質系細胞の有用性"}]},"item_type_id":"5","owner":"1","path":["1642","1891"],"pubdate":{"attribute_name":"公開日","attribute_value":"2015-03-26"},"publish_date":"2015-03-26","publish_status":"0","recid":"13282","relation_version_is_last":true,"title":["神経再生における微小重力環境で培養した骨髄間質系細胞の有用性"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-06-21T06:00:28.013500+00:00"}