@inproceedings{oai:jaxa.repo.nii.ac.jp:00013288, author = {石原, 昭彦 and 永友, 文子 and 大平, 充宣 and Ishihara, Akihiko and Nagatomo, Fumiko and Ohira, Yoshinobu}, book = {宇宙利用シンポジウム, Space Utilization Research: Proceedings of Space Utilization Symposium}, month = {Mar}, note = {第25回宇宙利用シンポジウム(2009年1月14日-15日, 宇宙航空研究開発機構宇宙科学研究本部相模原キャンパス), The Twenty-fifth Space Utilization Symposium (January 14-15, 2009: ISAS/JAXA Sagamihara, Japan), Eight-week-old rats were subjected to hyperbaric exposure (950 mmHg) with high oxygen concentration (36 %) for 2 weeks, followed by hindlimb unloading for 2 weeks. The fiber type distributions, cross-sectional areas, and oxidative enzyme activities in the soleus muscles of these rats were compared with those of hindlimb-unloaded rats without hyperbaric oxygenation. A type shift of fibers from type I to type IIA and decreased fiber succinate dehydrogenase (oxidative enzyme) activity of the muscle exposed to hyperbaric oxygenation were inhibited after hindlimb unloading. In contrast, the fiber cross-sectional area of the muscle was not influenced by hyperbaric oxygenation. It is concluded that hyperbaric exposure with high oxygen concentration used in this study is effective to inhibit a decrease in oxidative metabolism of skeletal muscles, which is induced by unloading., 資料番号: AA0064297044}, publisher = {宇宙航空研究開発機構宇宙科学研究本部, Institute of Space and Astronautical Science, Japan Aerospace Exploration Agency (JAXA)}, title = {高気圧・高濃度酸素への曝露がラットヒラメ筋線維のサイズと酸化系酵素活性に及ぼす影響}, volume = {25}, year = {2009} }