@inproceedings{oai:jaxa.repo.nii.ac.jp:00013304, author = {奥野, 誠 and 稲葉, 一男 and 清水, 強 and 堂前, 雅史 and 藤ノ木, 政勝 and 最上, 義広 and 渡辺, 明彦 and 向井, 千夏 and Okuno, Makoto and Inaba, Kazuo and Shimizu, Tsuyoshi and Dohmae, Masashi and Fujinoki, Masakatsu and Mogami, Yoshihiro and Watanabe, Akihiko and Mukai, Chinatsu}, book = {宇宙利用シンポジウム, Space Utilization Research: Proceedings of Space Utilization Symposium}, month = {Mar}, note = {第25回宇宙利用シンポジウム(2009年1月14日-15日, 宇宙航空研究開発機構宇宙科学研究本部相模原キャンパス), The Twenty-fifth Space Utilization Symposium (January 14-15, 2009: ISAS/JAXA Sagamihara, Japan), We organized a working group for studying the reproduction and continuity of life under the space environment. The aim of our project this year is to get deeper insight into the effect of gravity on reproduction. We found that suppression of body weight together with the decrease in food intake of mice under the hyper gravity, 3G, where they lost appetite. The effect was more apparent in younger mice. Hormones that reduce appetite, such as insulin and leptin were not likely to work. These results suggest that unknown complicate mechanism should be involved. We found a phenomenon that sex hormone might affect the fertilization directly via regulating the hyper activation of sperm. In addition we propose a new method for assessing the spermatogenesis activity by measuring apoptosis in spermatogenesis by means of caspase activity. This technique revealed that the spermatogenesis was suppressed by 10 G hypergravity in medaka., 形態: カラー図版あり, 資料番号: AA0064297060}, publisher = {宇宙航空研究開発機構宇宙科学研究本部, Institute of Space and Astronautical Science, Japan Aerospace Exploration Agency (JAXA)}, title = {宇宙環境下における生殖・継世代研究の展開: V}, volume = {25}, year = {2009} }