@inproceedings{oai:jaxa.repo.nii.ac.jp:00013308,
 author = {植村, 寿公 and 大藪, 淑美 and 三島, 初 and 田中, 順三 and Uemura, Toshimasa and Ohyabu, Yoshimi and Mishima, Hajime and Tanaka, Junzo},
 book = {宇宙利用シンポジウム, Space Utilization Research: Proceedings of Space Utilization Symposium},
 month = {Mar},
 note = {第25回宇宙利用シンポジウム(2009年1月14日-15日, 宇宙航空研究開発機構宇宙科学研究本部相模原キャンパス), The Twenty-fifth Space Utilization Symposium (January 14-15, 2009: ISAS/JAXA Sagamihara, Japan), Recently we have developed a novel culture technique for rapid regeneration of three dimensional cartilage tissue from rabbit bone marrow cells and human patients' bone marrow cells using a rotation wall vessel (RWV) bioreactor. The purpose of this study is to elucidate the time course and special change of the applied mechanical stress to the cartilage tissue and differentiation process of the tissue formed by the RWV bioreactor, for planning the Space Utilization Research. We developed a novel system for PIV (particle imaging velocity) measurement of the RWV culture system.. By this system, the flow of the medium occurred in the RWV vessel was measured and the applied mechanical stress to the tissue was estimated. Combining with the special distribution of mRNA expressions of cartilage marker genes by LMD (laser microdisection) method, the relationship between mechanical stress to the tissue and its differentiation from mesenchymal stem cells could be interpreted., 形態: カラー図版あり, 資料番号: AA0064297064},
 publisher = {宇宙航空研究開発機構宇宙科学研究本部, Institute of Space and Astronautical Science, Japan Aerospace Exploration Agency (JAXA)},
 title = {間葉系幹細胞の擬微小重力環境下における分化、組織構築過程に関する研究},
 volume = {25},
 year = {2009}
}