{"created":"2023-06-20T14:45:48.622533+00:00","id":13311,"links":{},"metadata":{"_buckets":{"deposit":"c66b439d-4458-4145-a046-64651f0fff76"},"_deposit":{"created_by":1,"id":"13311","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"13311"},"status":"published"},"_oai":{"id":"oai:jaxa.repo.nii.ac.jp:00013311","sets":["1543:1633:1642","1887:1891"]},"author_link":["120819","120817","120816","120829","120825","120826","120824","120828","120827","120820","120830","120818","120822","120815","120821","120823"],"item_5_alternative_title_2":{"attribute_name":"その他のタイトル（英）","attribute_value_mlt":[{"subitem_alternative_title":"Studies of space radiation influences : An experiment of cell culture in Kibou of ISS"}]},"item_5_biblio_info_10":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2009-03","bibliographicIssueDateType":"Issued"},"bibliographicVolumeNumber":"25","bibliographic_titles":[{"bibliographic_title":"宇宙利用シンポジウム"},{"bibliographic_title":"Space Utilization Research: Proceedings of Space Utilization Symposium","bibliographic_titleLang":"en"}]}]},"item_5_description_14":{"attribute_name":"会議概要（会議名, 開催地, 会期, 主催者等）","attribute_value_mlt":[{"subitem_description":"第25回宇宙利用シンポジウム(2009年1月14日-15日, 宇宙航空研究開発機構宇宙科学研究本部相模原キャンパス)","subitem_description_type":"Other"}]},"item_5_description_15":{"attribute_name":"会議概要（会議名, 開催地, 会期, 主催者等）（英）","attribute_value_mlt":[{"subitem_description":"The Twenty-fifth Space Utilization Symposium (January 14-15, 2009: ISAS/JAXA Sagamihara, Japan)","subitem_description_type":"Other"}]},"item_5_description_17":{"attribute_name":"抄録（英）","attribute_value_mlt":[{"subitem_description":"This paper is aimed to introduce how our developing methodologies for both loss of heterozygosity (LOH) analysis and DNA double-strand break (DSB) repair estimation are applied to detect the biological effects of space radiation. Our space experiments using human cultured cells in Kibou Facility of International Space Station (ISS) are planned to detect mutagenic effects (i), combined effects of radiation with micro gravity (ii), and radioadaptive response (iii). After cell recovery to the earth, we plan to do the following approaches for the above three biological effects: i) an LOH analysis for the mutants induced after the incubation of recovered frozen-cells exposed to low-dose space radiation during the 3 months preservation in ISS, ii) an examination for the existence of combined effects by comparing the mutation inductions between the cells incubated in ISS for ca. １ week under 1 G and those incubated under micro G, and iii) an estimation of the radioadaptive response from determination of the repair efficiencies of DSB introduced at the specific site of chromosome in the recovered cell.","subitem_description_type":"Other"}]},"item_5_description_18":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"形態: カラー図版あり","subitem_description_type":"Other"}]},"item_5_description_32":{"attribute_name":"資料番号","attribute_value_mlt":[{"subitem_description":"資料番号: AA0064297067","subitem_description_type":"Other"}]},"item_5_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"宇宙航空研究開発機構宇宙科学研究本部"}]},"item_5_publisher_9":{"attribute_name":"出版者（英）","attribute_value_mlt":[{"subitem_publisher":"Institute of Space and Astronautical Science, Japan Aerospace Exploration Agency (JAXA)"}]},"item_5_source_id_24":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AN10324210","subitem_source_identifier_type":"NCID"}]},"item_5_text_6":{"attribute_name":"著者所属","attribute_value_mlt":[{"subitem_text_value":"理化学研究所"},{"subitem_text_value":"理化学研究所"},{"subitem_text_value":"奈良県立医科大学"},{"subitem_text_value":"奈良県立医科大学"},{"subitem_text_value":"宇宙航空研究開発機構"},{"subitem_text_value":"宇宙航空研究開発機構"},{"subitem_text_value":"日本宇宙フォーラム"},{"subitem_text_value":"日本宇宙フォーラム"}]},"item_5_text_7":{"attribute_name":"著者所属（英）","attribute_value_mlt":[{"subitem_text_language":"en","subitem_text_value":"Institute of Physical and Chemical Research (RIKEN)"},{"subitem_text_language":"en","subitem_text_value":"Institute of Physical and Chemical Research (RIKEN)"},{"subitem_text_language":"en","subitem_text_value":"Nara Medical University"},{"subitem_text_language":"en","subitem_text_value":"Nara Medical University"},{"subitem_text_language":"en","subitem_text_value":"Japan Aerospace Exploration Agency (JAXA)"},{"subitem_text_language":"en","subitem_text_value":"Japan Aerospace Exploration Agency (JAXA)"},{"subitem_text_language":"en","subitem_text_value":"Japan Space Forum"},{"subitem_text_language":"en","subitem_text_value":"Japan Space Forum"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"谷田貝, 文夫"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"榎本, 秀一"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"高橋, 昭久"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"大西, 武雄"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"石岡, 憲昭"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"大森, 克徳"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"嶋津, 徹"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"鈴木, ひろみ"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Yatagai, Fumio","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Enomoto, Shuichi","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Takahashi, Akihisa","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Onishi, Takeo","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Ishioka, Noriaki","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Omori, Katsunori","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Shimazu, Toru","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Suzuki, Hiromi","creatorNameLang":"en"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-01-20"}],"displaytype":"detail","filename":"64297067.pdf","filesize":[{"value":"477.7 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"64297067.pdf","url":"https://jaxa.repo.nii.ac.jp/record/13311/files/64297067.pdf"},"version_id":"575a7538-5e83-4bbd-a5b2-44c4ba4ec656"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"space radiation, microgravity, human cells, LOH, adaptive response","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"conference paper","resourceuri":"http://purl.org/coar/resource_type/c_5794"}]},"item_title":"ISSきぼう棟内での細胞培養実験による宇宙放射線影響研究","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"ISSきぼう棟内での細胞培養実験による宇宙放射線影響研究"}]},"item_type_id":"5","owner":"1","path":["1642","1891"],"pubdate":{"attribute_name":"公開日","attribute_value":"2015-03-26"},"publish_date":"2015-03-26","publish_status":"0","recid":"13311","relation_version_is_last":true,"title":["ISSきぼう棟内での細胞培養実験による宇宙放射線影響研究"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-06-21T05:59:36.877766+00:00"}