{"created":"2023-06-20T14:45:56.908838+00:00","id":13446,"links":{},"metadata":{"_buckets":{"deposit":"2c366d15-5c02-4ec7-b1da-87e6003790f4"},"_deposit":{"created_by":1,"id":"13446","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"13446"},"status":"published"},"_oai":{"id":"oai:jaxa.repo.nii.ac.jp:00013446","sets":["1543:1633:1643","1887:1891"]},"author_link":["122537","122531","122535","122527","122529","122523","122526","122533","122538","122528","122525","122536","122539","122530","122534","122522","122524","122521","122532","122520"],"item_5_alternative_title_2":{"attribute_name":"その他のタイトル（英）","attribute_value_mlt":[{"subitem_alternative_title":"The importance of space rodent experiments"}]},"item_5_biblio_info_10":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2008-03","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"263","bibliographicPageStart":"262","bibliographic_titles":[{"bibliographic_title":"宇宙利用シンポジウム　第24回　平成19年度"},{"bibliographic_title":"Space Utilization Research: Proceedings of the Twenty-fourth Space Utilization Symposium","bibliographic_titleLang":"en"}]}]},"item_5_description_17":{"attribute_name":"抄録（英）","attribute_value_mlt":[{"subitem_description":"Like every other living creature we know of, humans evolved at the bottom of a gravity well. We take the Earth's tug for granted, and so do our bodies. When humans go into space, weightlessness itself is the most important and the most obvious influence on life. Especially, for space missions of several years in duration, the biggest problem that must be overcome is the harmful effects of weightlessness on the human body. These effects include loss of bone density, muscle mass and red blood cells, fluid shifting from the lower to upper body, cardiovascular and sensory-motor deconditioning and changes in the immune system. Such reactions by the body might be appropriate for zero-gravity flight, but are inappropriate for return to the surface of our planet or another planet. For centuries humans have observed animals in order to understand aspects of human biology and function. In modern times, animal research is the gold standard for basic biology and medicine. With animal subjects it is possible to control and reproduce environmental conditions, subject state and protocol, a set of advantages that are often difficult if not impossible to achieve with human subjects. There are needs for sufficient sample size and appropriate experimental timelines that can only be addressed using particular animal systems. Many studies require post-mortem analysis. Moreover, ethical considerations surrounding invasive procedures necessitate the use of non-human subjects. In space biology also, the use of animals and medicine is the most important measures to approach the problems mentioned above. So, to cite the indispensability of space animal experiments for achieving the long-term human space missions, we have been accumulating the references and information of this kind and been summing up each application case for the human physiological deconditionings in space. Simultaneously, in order to acquire the opportunities of space animal experiments for Japanese researchers continually, and to contribute the space biology, we have been seeking suitable space experiment platforms including not only the ISS (International Space Station) but also biosatellites. Currently, the possibility of collaboration between Japan and Europe has been examined in respect to the participation of Japanese researchers in rodent space experiments on the Russian Biosatellite 'Bion' or 'Foton' missions (flight planned NET 2010).","subitem_description_type":"Other"}]},"item_5_description_32":{"attribute_name":"資料番号","attribute_value_mlt":[{"subitem_description":"資料番号: AA0063706070","subitem_description_type":"Other"}]},"item_5_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"宇宙航空研究開発機構宇宙科学研究本部"}]},"item_5_publisher_9":{"attribute_name":"出版者（英）","attribute_value_mlt":[{"subitem_publisher":"Institute of Space and Astronautical Science, Japan Aerospace Exploration Agency (JAXA/ISAS)"}]},"item_5_text_6":{"attribute_name":"著者所属","attribute_value_mlt":[{"subitem_text_value":"福島県立医科大学 医学部"},{"subitem_text_value":"宇宙航空研究開発機構"},{"subitem_text_value":"東京大学 大学院総合文化研究科"},{"subitem_text_value":"京都大学 大学院人間・環境学研究科"},{"subitem_text_value":"奈良県立医科大学"},{"subitem_text_value":"大阪大学 医学部"},{"subitem_text_value":"東京大学 大学院総合文化研究科"},{"subitem_text_value":"東京医科歯科大学 大学院医歯学総合研究科"},{"subitem_text_value":"諏訪マタニティークリニック 附属清水宇宙生理学研究所"},{"subitem_text_value":"北海道立衛生研究所"}]},"item_5_text_7":{"attribute_name":"著者所属（英）","attribute_value_mlt":[{"subitem_text_language":"en","subitem_text_value":"Fukushima Medical University School of Medicine"},{"subitem_text_language":"en","subitem_text_value":"Japan Aerospace Exploration Agency"},{"subitem_text_language":"en","subitem_text_value":"University of Tokyo Graduate School of Arts and Sciences"},{"subitem_text_language":"en","subitem_text_value":"Kyoto University Graduate School of Human and Environmental Studies"},{"subitem_text_language":"en","subitem_text_value":"Nara Medical University"},{"subitem_text_language":"en","subitem_text_value":"Osaka University Faculty of Medicine"},{"subitem_text_language":"en","subitem_text_value":"University of Tokyo Graduate School of Arts and Sciences"},{"subitem_text_language":"en","subitem_text_value":"Tokyo Medical and Dental University Graduate School of Medicine and Dentistry"},{"subitem_text_language":"en","subitem_text_value":"Suwa Maternity Clinic Shimizu Institute of Space Physiology"},{"subitem_text_language":"en","subitem_text_value":"Hokkaido Institute of Public Health"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"片平, 清昭"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"中野, 完"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"跡見, 順子"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"石原, 昭彦"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"大西, 武雄"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"大平, 充宣"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"奥野, 誠"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"粂井, 康宏"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"清水, 強"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"矢野, 昭起"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Katahira, Kiyoaki","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Nakano, Tamotsu","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Atomi, Yoriko","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Ishihara, Akihiko","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Onishi, Takeo","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Ohira, Yoshinobu","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Okuno, Makoto","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Kumei, Yasuhiro","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Shimizu, Tsuyoshi","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Yano, Shoki","creatorNameLang":"en"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-01-20"}],"displaytype":"detail","filename":"63706070.pdf","filesize":[{"value":"263.2 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system","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"exobiology","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"biosatellite","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"weightlessness","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"artificial gravity","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"gravitational effect","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Bion","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Foton","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"conference 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