@inproceedings{oai:jaxa.repo.nii.ac.jp:00013458, author = {神谷, 厚範 and 上村, 和紀 and 杉町, 勝 and Kamiya, Atsunori and Uemura, Kazunori and Sugimachi, Masaru}, book = {宇宙利用シンポジウム 第24回 平成19年度, Space Utilization Research: Proceedings of the Twenty-fourth Space Utilization Symposium}, month = {Mar}, note = {Since a health care of astronauts is important for the human space development in the 21st century, it is ideal to manage the medical treatment in space by using cardiovascular medicine on the Earth. However, since cardiovascular medicine requires special techniques and knowledge, most of astronauts cannot learn it easily. Therefore, the present study has developed the automated remote medical system in space to optimize hemodynamics in heart failure (J Appl Physiol 2006). The system diagnoses hemodynamics by receiving measured hemodynamics parameters and quantifies cardiovascular mechanical properties from the parameters. Based upon the diagnosis, the system calculates and sends command signals to treatment equipments (drug infusion pump), and controls pumping ability by dobutamine, stressed blood volume by dextran and arterial resistance by nitroprusside/norepinephrine. By using the closed-loop circuit (biosignal-diagnosis- treatment), this system restored all mechanical properties (pumping ability, stressed blood volume, arterial resistance), and normalized arterial pressure, left atrial pressure and cardiac output in anesthetized animals with acute decompensated heart failure (n = 10) and cardiogenic shock (n = 6). The system has the ability to remote update the treatment algorithm. This system began the remote space medicine that supports human development to space. In addition, this system would be useful to support the medical treatment on the Earth, particularly in underpopulated area., 資料番号: AA0063706082}, pages = {293--294}, publisher = {宇宙航空研究開発機構宇宙科学研究本部, Institute of Space and Astronautical Science, Japan Aerospace Exploration Agency (JAXA/ISAS)}, title = {宇宙遠隔自動治療システムの開発}, year = {2008} }