{"created":"2023-06-20T14:45:58.158721+00:00","id":13470,"links":{},"metadata":{"_buckets":{"deposit":"15594651-bca2-49d8-a789-fb97a8900c42"},"_deposit":{"created_by":1,"id":"13470","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"13470"},"status":"published"},"_oai":{"id":"oai:jaxa.repo.nii.ac.jp:00013470","sets":["1543:1633:1643","1887:1891"]},"author_link":["122865","122863","122869","122870","122866","122864","122861","122862","122860","122867","122868","122871"],"item_5_alternative_title_2":{"attribute_name":"その他のタイトル（英）","attribute_value_mlt":[{"subitem_alternative_title":"An effort for detecting influences of low-dose ionizing radiation as adaptive response"}]},"item_5_biblio_info_10":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2008-03","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"334","bibliographicPageStart":"333","bibliographic_titles":[{"bibliographic_title":"宇宙利用シンポジウム　第24回　平成19年度"},{"bibliographic_title":"Space Utilization Research: Proceedings of the Twenty-fourth Space Utilization Symposium","bibliographic_titleLang":"en"}]}]},"item_5_description_17":{"attribute_name":"抄録（英）","attribute_value_mlt":[{"subitem_description":"DNA (DeoxyriboNucleic Acid) Double-Strand Break (DSB) was introduced by the I-Sce I expression vector, pCBASce. Repair of DSB introduced by the I-SceI expression vector at the tk+ allele in human lymphoblstoid TK6 cell line, TSCE5, was measured by induction of TK-deficient mutants. Similarly we also measured the revertants due to such repair in its compound heterozygote (tk-/-) cell line, TSCER2, which carried an additional point-mutation in exon 5. The former and later measurements reflect the DSB repair efficiency due to DNA Non-Homologous End-Joining (NHEJ) and Homologous Recombination (HR), respectively. The pre-treatment, C-ion-irradiation of frozen cells, TSCE5 and TSCER2 with 50 mGy enhanced DSB repair due to both pathways of NHEJ and HR, 2 to 3-fold. This kind of adaptive response might be observed with the cells recovered from the long preservation under the frozen status in ISS (International Space Station).","subitem_description_type":"Other"}]},"item_5_description_32":{"attribute_name":"資料番号","attribute_value_mlt":[{"subitem_description":"資料番号: AA0063706094","subitem_description_type":"Other"}]},"item_5_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"宇宙航空研究開発機構宇宙科学研究本部"}]},"item_5_publisher_9":{"attribute_name":"出版者（英）","attribute_value_mlt":[{"subitem_publisher":"Institute of Space and Astronautical Science, Japan Aerospace Exploration Agency (JAXA/ISAS)"}]},"item_5_text_6":{"attribute_name":"著者所属","attribute_value_mlt":[{"subitem_text_value":"理化学研究所"},{"subitem_text_value":"国立医薬品食品衛生研究所"},{"subitem_text_value":"宇宙航空研究開発機構 宇宙科学研究本部"},{"subitem_text_value":"宇宙航空研究開発機構 宇宙科学研究本部"},{"subitem_text_value":"日本宇宙フォーラム"},{"subitem_text_value":"日本宇宙フォーラム"}]},"item_5_text_7":{"attribute_name":"著者所属（英）","attribute_value_mlt":[{"subitem_text_language":"en","subitem_text_value":"Institute of Physical and Chemical Research"},{"subitem_text_language":"en","subitem_text_value":"National Institute of Health Sciences"},{"subitem_text_language":"en","subitem_text_value":"Japan Aerospace Exploration Agency Institute of Space and Astronautical Science"},{"subitem_text_language":"en","subitem_text_value":"Japan Aerospace Exploration Agency Institute of Space and Astronautical Science"},{"subitem_text_language":"en","subitem_text_value":"Japan Space Forum"},{"subitem_text_language":"en","subitem_text_value":"Japan Space Forum"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"谷田貝, 文夫"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"本間, 正充"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"石岡, 憲昭"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"大森, 克徳"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"嶋津, 徹"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"鈴木, ひろみ"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Yatagai, Fumio","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Honma, Masamitsu","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Ishioka, Noriaki","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Omori, Katsunori","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Shimazu, Toru","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Suzuki, Hiromi","creatorNameLang":"en"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-01-20"}],"displaytype":"detail","filename":"63706094.pdf","filesize":[{"value":"298.6 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"63706094.pdf","url":"https://jaxa.repo.nii.ac.jp/record/13470/files/63706094.pdf"},"version_id":"e6c1ee3a-8f81-494a-b5d9-dc7f7572c4fc"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"血液細胞","subitem_subject_scheme":"Other"},{"subitem_subject":"X線照射","subitem_subject_scheme":"Other"},{"subitem_subject":"放射線影響","subitem_subject_scheme":"Other"},{"subitem_subject":"国際宇宙ステーション","subitem_subject_scheme":"Other"},{"subitem_subject":"宇宙線","subitem_subject_scheme":"Other"},{"subitem_subject":"リンパ芽球腫","subitem_subject_scheme":"Other"},{"subitem_subject":"適応応答","subitem_subject_scheme":"Other"},{"subitem_subject":"2重鎖開裂","subitem_subject_scheme":"Other"},{"subitem_subject":"DSB","subitem_subject_scheme":"Other"},{"subitem_subject":"DSN修復","subitem_subject_scheme":"Other"},{"subitem_subject":"突然変異誘発","subitem_subject_scheme":"Other"},{"subitem_subject":"適応","subitem_subject_scheme":"Other"},{"subitem_subject":"放射線量","subitem_subject_scheme":"Other"},{"subitem_subject":"突然変異","subitem_subject_scheme":"Other"},{"subitem_subject":"培養細胞","subitem_subject_scheme":"Other"},{"subitem_subject":"blood cell","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"X-ray irradiation","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"radiation effect","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"International Space Station","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"cosmic ray","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"lymphoblastoid","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"adaptive response","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"double-strand break","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"DSB","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"DSB repair","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"mutagenesis","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"adaptation","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"radiation dosage","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"mutation","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"cultured cell","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"conference 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