{"created":"2023-06-20T14:46:03.323840+00:00","id":13573,"links":{},"metadata":{"_buckets":{"deposit":"e0ff645f-7714-4f51-8408-4ffbfa0c2347"},"_deposit":{"created_by":1,"id":"13573","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"13573"},"status":"published"},"_oai":{"id":"oai:jaxa.repo.nii.ac.jp:00013573","sets":["1543:1633:1644","1887:1891"]},"author_link":["123975","123981","123979","123976","123980","123977","123974","123978"],"item_5_alternative_title_2":{"attribute_name":"その他のタイトル（英）","attribute_value_mlt":[{"subitem_alternative_title":"Autonomic regulation of the heart under microgravity"}]},"item_5_biblio_info_10":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2007-03","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"268","bibliographicPageStart":"267","bibliographic_titles":[{"bibliographic_title":"宇宙利用シンポジウム　第23回　平成18年度"},{"bibliographic_title":"Space Utilization Research: Proceedings of the Twenty-third Space Utilization Symposium","bibliographic_titleLang":"en"}]}]},"item_5_description_17":{"attribute_name":"抄録（英）","attribute_value_mlt":[{"subitem_description":"We used transgenic mouse models with either disrupted (AC5KO) or overexpressed AC5 in the heart (AC5TG), and analyzed Heart Rate Variability (HRV) in pre-microgravity level flight, under microgravity, and in post-microgravity level flight during parabolic flight. Heart rate under microgravity became lower than that in pre-microgravity level flight in Wild Type (WT) and AC5TG while it was unchanged in AC5KO. The ratio between Low Frequency (LF) and High Frequency (HF) in HRV analysis became significantly lower under microgravity in WT and AC5TG while there was no such a decrease in AC5KO. Normalized HF became significantly greater in WT under microgravity, and became even greater in AC5TG. In contrast, there was no such increase in AC5KO under microgravity. Accordingly, changes in autonomic indexes in response to microgravity were augmented in AC5TG while attenuated in AC5KO, suggesting that the amount of AC5 plays a major role in determining the magnitude of cardiac responses, at least, to microgravity.","subitem_description_type":"Other"}]},"item_5_description_32":{"attribute_name":"資料番号","attribute_value_mlt":[{"subitem_description":"資料番号: AA0063349075","subitem_description_type":"Other"}]},"item_5_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"宇宙航空研究開発機構宇宙科学研究本部"}]},"item_5_publisher_9":{"attribute_name":"出版者（英）","attribute_value_mlt":[{"subitem_publisher":"Institute of Space and Astronautical Science, Japan Aerospace Exploration Agency (JAXA/ISAS)"}]},"item_5_text_6":{"attribute_name":"著者所属","attribute_value_mlt":[{"subitem_text_value":"横浜市立大学 大学院医学研究科"},{"subitem_text_value":"横浜市立大学 大学院医学研究科"},{"subitem_text_value":"横浜市立大学 大学院医学研究科"},{"subitem_text_value":"横浜市立大学 大学院医学研究科"}]},"item_5_text_7":{"attribute_name":"著者所属（英）","attribute_value_mlt":[{"subitem_text_language":"en","subitem_text_value":"Yokohama City University School of Medicine"},{"subitem_text_language":"en","subitem_text_value":"Yokohama City University School of Medicine"},{"subitem_text_language":"en","subitem_text_value":"Yokohama City University School of Medicine"},{"subitem_text_language":"en","subitem_text_value":"Yokohama City University School of Medicine"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"石川, 義弘"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"南沢, 享"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"佐藤, 元彦"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"奥村, 敏"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Ishikawa, Yoshihiro","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Minamisawa, Susumu","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Sato, Motohiko","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Okumura, Satoshi","creatorNameLang":"en"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-01-20"}],"displaytype":"detail","filename":"63349075.pdf","filesize":[{"value":"272.7 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"63349075.pdf","url":"https://jaxa.repo.nii.ac.jp/record/13573/files/63349075.pdf"},"version_id":"21545fdb-3ac9-48cd-b3b4-4e825c32b64f"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"自律神経系","subitem_subject_scheme":"Other"},{"subitem_subject":"マウス","subitem_subject_scheme":"Other"},{"subitem_subject":"遺伝子導入マウス","subitem_subject_scheme":"Other"},{"subitem_subject":"アデニル酸シクラーゼ","subitem_subject_scheme":"Other"},{"subitem_subject":"心機能","subitem_subject_scheme":"Other"},{"subitem_subject":"心拍数","subitem_subject_scheme":"Other"},{"subitem_subject":"重力効果","subitem_subject_scheme":"Other"},{"subitem_subject":"微小重力","subitem_subject_scheme":"Other"},{"subitem_subject":"放物線飛行","subitem_subject_scheme":"Other"},{"subitem_subject":"心電図","subitem_subject_scheme":"Other"},{"subitem_subject":"起立耐性","subitem_subject_scheme":"Other"},{"subitem_subject":"圧反射","subitem_subject_scheme":"Other"},{"subitem_subject":"交感神経応答","subitem_subject_scheme":"Other"},{"subitem_subject":"副交感神経応答","subitem_subject_scheme":"Other"},{"subitem_subject":"autonomic nervous system","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"mouse","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"transgenic mouse","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"adenylyl cyclase","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"cardiac function","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"heart rate","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"gravitational effect","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"microgravity","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"parabolic flight","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"electrocardiography","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"orthostatic tolerance","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"baroreflex","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"symapathetic response","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"parasympathetic response","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"conference paper","resourceuri":"http://purl.org/coar/resource_type/c_5794"}]},"item_title":"微小重力下での自律神経による心機能制御の検討","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"微小重力下での自律神経による心機能制御の検討"}]},"item_type_id":"5","owner":"1","path":["1644","1891"],"pubdate":{"attribute_name":"公開日","attribute_value":"2015-03-26"},"publish_date":"2015-03-26","publish_status":"0","recid":"13573","relation_version_is_last":true,"title":["微小重力下での自律神経による心機能制御の検討"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-06-21T05:50:59.255814+00:00"}