@inproceedings{oai:jaxa.repo.nii.ac.jp:00013582,
 author = {三谷, 啓志 and 尾田, 正二 and 清木, 誠 and 亀井, 保博 and 舟山, 知夫 and 大森, 克徳 and 古賀, 章彦 and Mitani, Hiroshi and Oda, Shoji and FurutaniSeiki, Makoto and Kamei, Yasuhiro and Funayama, Tomoo and Omori, Katsunori and Koga, Akihiko},
 book = {宇宙利用シンポジウム　第23回　平成18年度, Space Utilization Research: Proceedings of the Twenty-third Space Utilization Symposium},
 month = {Mar},
 note = {During space flights, crew members are constantly exposed to space radiation. Such radiation damages the cellular DNA, and may induce mutations in germ cells. Medaka (Oryzias latipes) is a useful experimental fish and precise system to measure germ cell mutation induction by specific locus test was established and found that the spontaneous and gamma-ray induced mutation rates are very similar to those of mice. We are developing novel assay systems which can detect the germinal mutation using sperm genome. The point variation and frame shift variation will be detected by the high throughput SNPs (Single Nucleotide Polymorphisms) detection system. And the transgenic strains with visible fluorescent marker expressed in sperm can detect deletion-type mutations. These systems will enable a better assessment of the late genetic risk for humans in space and, in the long-term, will contribute to optimize radiation shielding for future space exploration missions., 資料番号: AA0063349084},
 pages = {295--297},
 publisher = {宇宙航空研究開発機構宇宙科学研究本部, Institute of Space and Astronautical Science, Japan Aerospace Exploration Agency (JAXA/ISAS)},
 title = {メダカを用いた宇宙環境放射線の経世代影響の評価法の開発},
 year = {2007}
}