{"created":"2023-06-20T14:46:03.711293+00:00","id":13582,"links":{},"metadata":{"_buckets":{"deposit":"288ef8fa-aa4c-470e-97b3-c505da1b8405"},"_deposit":{"created_by":1,"id":"13582","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"13582"},"status":"published"},"_oai":{"id":"oai:jaxa.repo.nii.ac.jp:00013582","sets":["1543:1633:1644","1887:1891"]},"author_link":["124101","124088","124093","124099","124096","124089","124090","124100","124091","124094","124095","124097","124092","124098"],"item_5_alternative_title_2":{"attribute_name":"その他のタイトル（英）","attribute_value_mlt":[{"subitem_alternative_title":"Novel assay for transgenerational effects of space radiation in Medaka"}]},"item_5_biblio_info_10":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2007-03","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"297","bibliographicPageStart":"295","bibliographic_titles":[{"bibliographic_title":"宇宙利用シンポジウム　第23回　平成18年度"},{"bibliographic_title":"Space Utilization Research: Proceedings of the Twenty-third Space Utilization Symposium","bibliographic_titleLang":"en"}]}]},"item_5_description_17":{"attribute_name":"抄録（英）","attribute_value_mlt":[{"subitem_description":"During space flights, crew members are constantly exposed to space radiation. Such radiation damages the cellular DNA, and may induce mutations in germ cells. Medaka (Oryzias latipes) is a useful experimental fish and precise system to measure germ cell mutation induction by specific locus test was established and found that the spontaneous and gamma-ray induced mutation rates are very similar to those of mice. We are developing novel assay systems which can detect the germinal mutation using sperm genome. The point variation and frame shift variation will be detected by the high throughput SNPs (Single Nucleotide Polymorphisms) detection system. And the transgenic strains with visible fluorescent marker expressed in sperm can detect deletion-type mutations. These systems will enable a better assessment of the late genetic risk for humans in space and, in the long-term, will contribute to optimize radiation shielding for future space exploration missions.","subitem_description_type":"Other"}]},"item_5_description_32":{"attribute_name":"資料番号","attribute_value_mlt":[{"subitem_description":"資料番号: AA0063349084","subitem_description_type":"Other"}]},"item_5_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"宇宙航空研究開発機構宇宙科学研究本部"}]},"item_5_publisher_9":{"attribute_name":"出版者（英）","attribute_value_mlt":[{"subitem_publisher":"Institute of Space and Astronautical Science, Japan Aerospace Exploration Agency (JAXA/ISAS)"}]},"item_5_text_6":{"attribute_name":"著者所属","attribute_value_mlt":[{"subitem_text_value":"東京大学 大学院新領域創成科学研究科"},{"subitem_text_value":"東京大学 大学院新領域創成科学研究科"},{"subitem_text_value":"科学技術振興機構 戦略的創造事業本部　研究推進部"},{"subitem_text_value":"京都大学 放射線生物研究センター"},{"subitem_text_value":"日本原子力研究開発機構 高崎量子応用研究所"},{"subitem_text_value":"宇宙航空研究開発機構"},{"subitem_text_value":"名古屋大学 大学院理学研究科"}]},"item_5_text_7":{"attribute_name":"著者所属（英）","attribute_value_mlt":[{"subitem_text_language":"en","subitem_text_value":"University of Tokyo Graduate School of Frontier Sciences"},{"subitem_text_language":"en","subitem_text_value":"University of Tokyo Graduate School of Frontier Sciences"},{"subitem_text_language":"en","subitem_text_value":"Japan Science and Technology Agency Department of Research Promotion, Office of Basic Research"},{"subitem_text_language":"en","subitem_text_value":"Kyoto University Radiation Biology Center"},{"subitem_text_language":"en","subitem_text_value":"Japan Atomic Energy Agency Takasaki Advanced Radiation Research Institute"},{"subitem_text_language":"en","subitem_text_value":"Japan Aerospace Exploration Agency"},{"subitem_text_language":"en","subitem_text_value":"Nagoya University Graduate School of Science"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"三谷, 啓志"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"尾田, 正二"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"清木, 誠"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"亀井, 保博"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"舟山, 知夫"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"大森, 克徳"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"古賀, 章彦"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Mitani, Hiroshi","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Oda, Shoji","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"FurutaniSeiki, Makoto","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Kamei, Yasuhiro","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Funayama, Tomoo","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Omori, Katsunori","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Koga, Akihiko","creatorNameLang":"en"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-01-20"}],"displaytype":"detail","filename":"63349084.pdf","filesize":[{"value":"829.1 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"63349084.pdf","url":"https://jaxa.repo.nii.ac.jp/record/13582/files/63349084.pdf"},"version_id":"1bb374c8-c652-475c-8061-40e5c6c61f0b"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"宇宙放射線","subitem_subject_scheme":"Other"},{"subitem_subject":"突然変異","subitem_subject_scheme":"Other"},{"subitem_subject":"継世代影響","subitem_subject_scheme":"Other"},{"subitem_subject":"メダカ","subitem_subject_scheme":"Other"},{"subitem_subject":"航空宇宙環境","subitem_subject_scheme":"Other"},{"subitem_subject":"放射線量","subitem_subject_scheme":"Other"},{"subitem_subject":"遺伝子","subitem_subject_scheme":"Other"},{"subitem_subject":"蛍光","subitem_subject_scheme":"Other"},{"subitem_subject":"放射線障害","subitem_subject_scheme":"Other"},{"subitem_subject":"ゲノム","subitem_subject_scheme":"Other"},{"subitem_subject":"魚","subitem_subject_scheme":"Other"},{"subitem_subject":"生殖細胞","subitem_subject_scheme":"Other"},{"subitem_subject":"精子","subitem_subject_scheme":"Other"},{"subitem_subject":"遺伝子導入魚","subitem_subject_scheme":"Other"},{"subitem_subject":"space radiation","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"mutation","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"transgenerational effect","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Oryzias latipes","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"aerospace environment","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"radiation dosage","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"gene","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"fluorescence","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"radiation damage","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"genome","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"fish","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"germ cell","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"sperm","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"transgenic fish","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"conference paper","resourceuri":"http://purl.org/coar/resource_type/c_5794"}]},"item_title":"メダカを用いた宇宙環境放射線の経世代影響の評価法の開発","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"メダカを用いた宇宙環境放射線の経世代影響の評価法の開発"}]},"item_type_id":"5","owner":"1","path":["1644","1891"],"pubdate":{"attribute_name":"公開日","attribute_value":"2015-03-26"},"publish_date":"2015-03-26","publish_status":"0","recid":"13582","relation_version_is_last":true,"title":["メダカを用いた宇宙環境放射線の経世代影響の評価法の開発"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-06-21T05:50:39.881373+00:00"}