@inproceedings{oai:jaxa.repo.nii.ac.jp:00013587, author = {古野, 伸明 and 田澤, 一朗 and 柏木, 啓子 and 新海, 正 and 吉留, 賢 and 渡部, 稔 and 山下, 雅道 and 柏木, 昭彦 and Furuno, Nobuaki and Tazawa, Ichiro and Kashiwagi, Keiko and Shinkai, Tadashi and Yoshitome, Satoshi and Watanabe, Minoru and Yamashita, Masamichi and Kashiwagi, Akihiko}, book = {宇宙利用シンポジウム 第23回 平成18年度, Space Utilization Research: Proceedings of the Twenty-third Space Utilization Symposium}, month = {Mar}, note = {Full-grown Xenopus oocytes arrest at the prophase of meiosis I. The hormone progesterone induces resumption of the meiotic cell cycle, leading to maturation of the oocyte into a fertilizable egg. We investigated the effect of hypergravity on Xenopus oocyte maturation. At the last meeting, we reported that hypergravity did not affect the initiation of maturation, whereas the progression of maturation was affected regarding the external appearance of the white spot. The present study examines changes in spindle morphology during Xenopus oocyte maturation. Cytological examination showed that spindle formation of meiosis II was largely inhibited, although meiosis I was successfully completed. These findings suggest that hypergravity inhibits the bipolar spindle formation of meiosis II, and hence adversely affects the process of oocyte maturation in Xenopus laevis., 資料番号: AA0063349089}, pages = {311--313}, publisher = {宇宙航空研究開発機構宇宙科学研究本部, Institute of Space and Astronautical Science, Japan Aerospace Exploration Agency (JAXA/ISAS)}, title = {アフリカツメガエル卵成熟過程に対する過重力の影響}, year = {2007} }