{"created":"2023-06-20T14:46:04.018822+00:00","id":13589,"links":{},"metadata":{"_buckets":{"deposit":"441a9904-8d2c-4617-a81f-66f44d1319a1"},"_deposit":{"created_by":1,"id":"13589","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"13589"},"status":"published"},"_oai":{"id":"oai:jaxa.repo.nii.ac.jp:00013589","sets":["1543:1633:1644","1887:1891"]},"author_link":["124187","124197","124178","124179","124183","124193","124182","124190","124191","124186","124194","124181","124195","124189","124185","124192","124196","124180","124188","124184"],"item_5_alternative_title_2":{"attribute_name":"その他のタイトル（英）","attribute_value_mlt":[{"subitem_alternative_title":"Space biology utilizing fish scale"}]},"item_5_biblio_info_10":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2007-03","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"321","bibliographicPageStart":"318","bibliographic_titles":[{"bibliographic_title":"宇宙利用シンポジウム　第23回　平成18年度"},{"bibliographic_title":"Space Utilization Research: Proceedings of the Twenty-third Space Utilization Symposium","bibliographic_titleLang":"en"}]}]},"item_5_description_17":{"attribute_name":"抄録（英）","attribute_value_mlt":[{"subitem_description":"In osteoclast activity during space flight, inconsistent results have been reported in an in vivo study while osteoblastic function is consistently reduced by space flight. Bone matrix is an important function in the response to physical stress. However, there is no suitable in vitro co-culture system of osteoblasts and osteoclasts including bone matrix. On the other hand, fish scale is a calcified tissue that contains osteoblasts, osteoclasts, and bone matrix, all of which are similar to those found in human bones. Recently, we developed a new in vitro model system using goldfish scale. This system can be used to simultaneously detect the activities of both scale osteoclasts and osteoblasts with tartrate-resistant acid phosphatase and alkaline phosphatase as the respective markers and precisely analyze the co-relationship between osteoblasts and osteoclasts. In our co-culture system, osteoblasts and osteoclasts reacted sensitively to several degrees of acceleration, ultrasound stimulation, and micro-gravity of 3D clinostat. Therefore, we strongly believe that our in vitro co-culture system is suitable model for the analysis of bone metabolism under micro-gravity, such as that experienced in space flight.","subitem_description_type":"Other"}]},"item_5_description_32":{"attribute_name":"資料番号","attribute_value_mlt":[{"subitem_description":"資料番号: AA0063349091","subitem_description_type":"Other"}]},"item_5_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"宇宙航空研究開発機構宇宙科学研究本部"}]},"item_5_publisher_9":{"attribute_name":"出版者（英）","attribute_value_mlt":[{"subitem_publisher":"Institute of Space and Astronautical Science, Japan Aerospace Exploration Agency (JAXA/ISAS)"}]},"item_5_text_6":{"attribute_name":"著者所属","attribute_value_mlt":[{"subitem_text_value":"金沢大学 自然計測応用研究センター"},{"subitem_text_value":"宇宙航空研究開発機構"},{"subitem_text_value":"東京大学 アイソトープ総合センター"},{"subitem_text_value":"金沢大学 大学院医学系研究科"},{"subitem_text_value":"金沢大学 大学院医学系研究科"},{"subitem_text_value":"鹿児島大学 大学院医歯学総合研究科"},{"subitem_text_value":"岡山大学 大学院医歯薬学総合研究科"},{"subitem_text_value":"早稲田大学 教育・総合科学学術院"},{"subitem_text_value":"富山大学 医学薬学研究部"},{"subitem_text_value":"富山大学 医学薬学研究部"}]},"item_5_text_7":{"attribute_name":"著者所属（英）","attribute_value_mlt":[{"subitem_text_language":"en","subitem_text_value":"Kanazawa University Institute of Nature and Environmental Technology"},{"subitem_text_language":"en","subitem_text_value":"Japan Aerospace Exploration Agency"},{"subitem_text_language":"en","subitem_text_value":"University of Tokyo Radioisotope Center"},{"subitem_text_language":"en","subitem_text_value":"Kanazawa University Graduate School of Medical Science"},{"subitem_text_language":"en","subitem_text_value":"Kanazawa University Graduate School of Medical Science"},{"subitem_text_language":"en","subitem_text_value":"Kagoshima University Graduate School of Medical and Dental Sciences"},{"subitem_text_language":"en","subitem_text_value":"Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences"},{"subitem_text_language":"en","subitem_text_value":"Waseda University Faculty of Education and Integral Arts and Science"},{"subitem_text_language":"en","subitem_text_value":"University of Toyama Graduate School of Medicine and Pharmaceutical Sciences"},{"subitem_text_language":"en","subitem_text_value":"University of Toyama Graduate School of Medicine and Pharmaceutical Sciences"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"鈴木, 信雄"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"大森, 克徳"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"井尻, 憲一"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"北村, 敬一郎"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"清水, 宣明"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"田畑, 純"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"池亀, 美華"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"中村, 正久"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"近藤, 隆"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"松田, 恒平"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Suzuki, Nobuo","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Omori, Katsunori","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Ijiri, Kenichi","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Kitamura, Keiichiro","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Shimizu, Nobuaki","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Tabata, Makoto J.","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Ikegame, Mika","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Nakamura, Masahisa","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Kondo, Takashi","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Matsuda, Kohei","creatorNameLang":"en"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-01-20"}],"displaytype":"detail","filename":"63349091.pdf","filesize":[{"value":"435.9 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"63349091.pdf","url":"https://jaxa.repo.nii.ac.jp/record/13589/files/63349091.pdf"},"version_id":"6c222e2a-f7bb-4f6a-a342-67126a4c552a"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"魚","subitem_subject_scheme":"Other"},{"subitem_subject":"魚類のウロコ","subitem_subject_scheme":"Other"},{"subitem_subject":"骨芽細胞","subitem_subject_scheme":"Other"},{"subitem_subject":"破骨細胞","subitem_subject_scheme":"Other"},{"subitem_subject":"宇宙生物学","subitem_subject_scheme":"Other"},{"subitem_subject":"高重力環境","subitem_subject_scheme":"Other"},{"subitem_subject":"超音波","subitem_subject_scheme":"Other"},{"subitem_subject":"クリノスタット","subitem_subject_scheme":"Other"},{"subitem_subject":"微小重力","subitem_subject_scheme":"Other"},{"subitem_subject":"骨","subitem_subject_scheme":"Other"},{"subitem_subject":"重力効果","subitem_subject_scheme":"Other"},{"subitem_subject":"機械的ストレス","subitem_subject_scheme":"Other"},{"subitem_subject":"エストローゲン受容体","subitem_subject_scheme":"Other"},{"subitem_subject":"酒石酸塩耐性酸性燐酸分解酵素","subitem_subject_scheme":"Other"},{"subitem_subject":"fish","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"fish scale","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"osteoblast","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"osteoclast","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"exobiology","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"high gravity environment","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"ultrasonic wave","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"clinostat","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"microgravity","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"bone","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"gravitational effect","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"mechanical stress","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"estrogen receptor","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"tartrate-resistant acid phosphatase","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"conference paper","resourceuri":"http://purl.org/coar/resource_type/c_5794"}]},"item_title":"魚類のウロコを用いた宇宙生物学的研究","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"魚類のウロコを用いた宇宙生物学的研究"}]},"item_type_id":"5","owner":"1","path":["1644","1891"],"pubdate":{"attribute_name":"公開日","attribute_value":"2015-03-26"},"publish_date":"2015-03-26","publish_status":"0","recid":"13589","relation_version_is_last":true,"title":["魚類のウロコを用いた宇宙生物学的研究"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-06-21T05:50:25.910715+00:00"}