@inproceedings{oai:jaxa.repo.nii.ac.jp:00013590, author = {井尻, 憲一 and 水野, 利恵 and Ijiri, Kenichi and Mizuno, Rie}, book = {宇宙利用シンポジウム 第23回 平成18年度, Space Utilization Research: Proceedings of the Twenty-third Space Utilization Symposium}, month = {Mar}, note = {In rodents, the immediate-early genes serve as useful neurobiological tools for mapping brain activity induced by gravity changes. In this study, we have examined brain activity related to gravity perception of medaka (Oryzias latipes) by use of c-fos expression. Fish were continuously exposed to 3 G hypergravity by centrifugation. The distribution of its transcripts within brains was analyzed by an in situ hybridization method. The 3 G-treated medakas displayed c-fos mRNA positive cells in their brain regions, which are related to vestibular function. Using the immunohistochemistry technique, the distribution and number of cells positive for c-Fos proteins were studied. The results showed that wild-type and mutant strain (ha) respond differently to 3 G exposure both quantitatively and qualitatively., 資料番号: AA0063349092}, pages = {322--325}, publisher = {宇宙航空研究開発機構宇宙科学研究本部, Institute of Space and Astronautical Science, Japan Aerospace Exploration Agency (JAXA/ISAS)}, title = {過重力刺激によるc-Fosタンパク質の脳内出現部位:マウスからメダカへ}, year = {2007} }