@inproceedings{oai:jaxa.repo.nii.ac.jp:00013614,
 author = {長沼, 毅 and 伊村, 智 and 岩月, 輝希 and 川久保, 忠通 and 小林, 憲正 and 三枝, 誠行 and 佐藤, 皓 and 嶋田, 和人 and 白壁, 義久 and 高野, 淑識 and Naganuma, Takeshi and Imura, Satoshi and Iwatsuki, Teruki and Kawakubo, Tadamichi and Kobayashi, Kensei and Saigusa, Masayuki and Sato, Hikaru and Shimada, Kazuhito and Shirakabe, Yoshihisa and Takano, Yoshinori},
 book = {宇宙利用シンポジウム　第23回　平成18年度, Space Utilization Research: Proceedings of the Twenty-third Space Utilization Symposium},
 month = {Mar},
 note = {Microbial cells were irradiated with high-dose X-ray (0.2 nm, 500 R/s) for 0 to 5 min to examine their survivability based on the biological 'energy currency', i.e., Adenosine 5'-Triphosphate (ATP), and the Colony-Forming Units (CFU). The well-known radiation-resistant bacterium, Deinococcus radiodurans, and the normal and mini cells of Escherichia coli X-1488 were used for the irradiation tests. Minicells are known to lack genomic DNA, and were thus used to examine the effect of X-ray on non-DNA damages, while X-ray causes indirect (e.g., via OH-radical formation) damages to DNA. The results were: (1) ATP showed highest survivability in the D. radiodurans cells, followed by the normal E. coli cells; (2) CFU of D. radiodurans showed highest survivability, too; and, (3) ATP and CFU of minicells showed rapid decrease despite absence of DNA to-be-damaged by X-ray irradiation. These results suggest that non-DNA damages (probably damages against proteins and/or membrane) affect the viability of minicells. Direct effects of X-ray irradiation against non-cellular ATP and other biomolecules should be assessed in future studies., 資料番号: AA0063349116},
 pages = {406--409},
 publisher = {宇宙航空研究開発機構宇宙科学研究本部, Institute of Space and Astronautical Science, Japan Aerospace Exploration Agency (JAXA/ISAS)},
 title = {隕石・彗星内ハビタブルゾーンにおける大線量X線照射の影響評価に関する予察的研究},
 year = {2007}
}