@inproceedings{oai:jaxa.repo.nii.ac.jp:00013675, author = {宮本, 武典 and 土田, 晴美 and 藤原, 宏子 and 佐藤, 亮平 and Miyamoto, Takenori and Tsuchida, Harumi and Eda‐Fijiwara, Hiroko and Sato, Ryohei}, book = {宇宙利用シンポジウム, Space Utilization Research: Proceedings of Space Utilization Symposium}, month = {Mar}, note = {第22回宇宙利用シンポジウム(2006年1月17日-19日, 日本学術会議6階会議室 六本木、東京), The Twenty-second Space Utilization Symposium (January 17-19, 2006: Science Council of Japan, Roppongi, Tokyo, Japan), We compared among the effects of gravitational disturbance before and after conditioned stimuli on acquisition and retention of the conditioned taste aversion (CTA) paradigm as a model of emotional learning and memory. When the gravitational disturbance by 3D clinostat was applied between 0.2% sodium saccharin as a conditioned stimulus (CS) and an i.p. injection of 0.15 M LiCl as an unconditioned stimulus (US), both acquisition and retention of CTA memory (CTAM) was suppressed. On the other hand, the gravitational disturbance before CS suppressed water-intake but not CTA. Furthermore, after CTAM acquisition with the gravitational disturbance, expression of an immediately early gene, c-fos was expressed in the dorsal tegmental area but not in the vestibular nuclei regardless of presence of gravitational disturbance. These results suggest possibility that the gravitational disturbance by clinostat was not accepted through the vestibular system but directly by the ascending activating system in the brain stem., 共催: 日本学術会議, Meeting sponsors: The Science Council of Japan, The Institute of Space and Astronautical Science, Japan Aerospace Exploration Agency (ISAS)(JAXA), 資料番号: AA0064113058}, publisher = {宇宙航空研究開発機構宇宙科学研究本部, Institute of Space and Astronautical Science, Japan Aerospace Exploration Agency (JAXA)}, title = {マウス味覚嫌悪学習の条件刺激前後での重力攪乱の影響の比較}, volume = {22}, year = {2006} }