{"created":"2023-06-20T14:46:07.985582+00:00","id":13680,"links":{},"metadata":{"_buckets":{"deposit":"12e82423-24d0-4e5c-afe4-616e7668b1c3"},"_deposit":{"created_by":1,"id":"13680","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"13680"},"status":"published"},"_oai":{"id":"oai:jaxa.repo.nii.ac.jp:00013680","sets":["1543:1633:1645","1887:1891"]},"author_link":["125251","125249","125250","125253","125252","125246","125247","125248"],"item_5_alternative_title_2":{"attribute_name":"その他のタイトル（英）","attribute_value_mlt":[{"subitem_alternative_title":"Low dose radiation-responsive proteins in cultured astrocytes"}]},"item_5_biblio_info_10":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2006-03","bibliographicIssueDateType":"Issued"},"bibliographicVolumeNumber":"22","bibliographic_titles":[{"bibliographic_title":"宇宙利用シンポジウム"},{"bibliographic_title":"Space Utilization Research: Proceedings of Space Utilization Symposium","bibliographic_titleLang":"en"}]}]},"item_5_description_14":{"attribute_name":"会議概要（会議名, 開催地, 会期, 主催者等）","attribute_value_mlt":[{"subitem_description":"第22回宇宙利用シンポジウム(2006年1月17日-19日, 日本学術会議6階会議室 六本木、東京)","subitem_description_type":"Other"}]},"item_5_description_15":{"attribute_name":"会議概要（会議名, 開催地, 会期, 主催者等）（英）","attribute_value_mlt":[{"subitem_description":"The Twenty-second Space Utilization Symposium (January 17-19, 2006: Science Council of Japan, Roppongi, Tokyo, Japan)","subitem_description_type":"Other"}]},"item_5_description_17":{"attribute_name":"抄録（英）","attribute_value_mlt":[{"subitem_description":"Ionizing radiation causes various damages, carcinogenesis or cell death. However, low dose irradiation is reported to give rise to adaptive responses. We have reported that radiation adaptive response was observed in cultured astrocytes from young rats, and that the response was decreased with aging. In order to investigate the mechanisms of radiation adaptive response in cultured astrocytes, in the present study, we analyzed the variant expressions and phosphorylation of proteins in cell using proteomics. As a result, the fragmentation of elongation factor 2 was temporarily increased and elongation factor 1-beta was de-phosphorylated after low dose irradiation.","subitem_description_type":"Other"}]},"item_5_description_18":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"共催: 日本学術会議","subitem_description_type":"Other"}]},"item_5_description_19":{"attribute_name":"内容記述（英）","attribute_value_mlt":[{"subitem_description":"Meeting sponsors: The Science Council of Japan, The Institute of Space and Astronautical Science, Japan Aerospace Exploration Agency (ISAS)(JAXA)","subitem_description_type":"Other"}]},"item_5_description_32":{"attribute_name":"資料番号","attribute_value_mlt":[{"subitem_description":"資料番号: AA0064113063","subitem_description_type":"Other"}]},"item_5_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"宇宙航空研究開発機構宇宙科学研究本部"}]},"item_5_publisher_9":{"attribute_name":"出版者（英）","attribute_value_mlt":[{"subitem_publisher":"Institute of Space and Astronautical Science, Japan Aerospace Exploration Agency (JAXA)"}]},"item_5_source_id_24":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AN10324210","subitem_source_identifier_type":"NCID"}]},"item_5_text_6":{"attribute_name":"著者所属","attribute_value_mlt":[{"subitem_text_value":"東京都老人総合研究所"},{"subitem_text_value":"東京都老人総合研究所"},{"subitem_text_value":"東京都老人総合研究所"},{"subitem_text_value":"東京都老人総合研究所"}]},"item_5_text_7":{"attribute_name":"著者所属（英）","attribute_value_mlt":[{"subitem_text_language":"en","subitem_text_value":"Tokyo Metropolitan Institute of Gerontology"},{"subitem_text_language":"en","subitem_text_value":"Tokyo Metropolitan Institute of Gerontology"},{"subitem_text_language":"en","subitem_text_value":"Tokyo Metropolitan Institute of Gerontology"},{"subitem_text_language":"en","subitem_text_value":"Tokyo Metropolitan Institute of Gerontology"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"三浦, ゆり"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"加納, まゆみ"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"鈴木, 捷三"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"戸田, 年総"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Miura, Yuri","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Kano, Mayumi","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Suzuki, Shozo","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Toda, Tosifusa","creatorNameLang":"en"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-01-20"}],"displaytype":"detail","filename":"64113063.pdf","filesize":[{"value":"152.2 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"64113063.pdf","url":"https://jaxa.repo.nii.ac.jp/record/13680/files/64113063.pdf"},"version_id":"0825d915-43bf-4b39-9ab3-679b2a82c2af"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"low dose radiation, radiation adaptive response, proteomics, phosphorylation, aging, 2-D PAGE","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"conference paper","resourceuri":"http://purl.org/coar/resource_type/c_5794"}]},"item_title":"培養アストロサイトにおける低線量放射線応答タンパクの解析","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"培養アストロサイトにおける低線量放射線応答タンパクの解析"}]},"item_type_id":"5","owner":"1","path":["1645","1891"],"pubdate":{"attribute_name":"公開日","attribute_value":"2015-03-26"},"publish_date":"2015-03-26","publish_status":"0","recid":"13680","relation_version_is_last":true,"title":["培養アストロサイトにおける低線量放射線応答タンパクの解析"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-06-21T05:47:27.519136+00:00"}