@inproceedings{oai:jaxa.repo.nii.ac.jp:00013681,
 author = {谷田貝, 文夫 and 梅林, 志浩 and 菅沢, 薫 and 花岡, 文雄 and 岩木, 正哉 and 本間, 正充 and 石岡, 憲昭 and 嶋津, 徹 and 鈴木, ひろみ and Yatagai, Fumio and Umebayashi, Yukihiro and Sugasawa, Kaoru and Hanaoka, Fumio and Iwaki, Masaya and Honma, Masamitsu and Ishioka, Noriaki and Shimazu, Toru and Suzuki, Hiromi},
 book = {宇宙利用シンポジウム, Space Utilization Research: Proceedings of Space Utilization Symposium},
 month = {Mar},
 note = {第22回宇宙利用シンポジウム(2006年1月17日-19日, 日本学術会議6階会議室 六本木、東京), The Twenty-second Space Utilization Symposium (January 17-19, 2006: Science Council of Japan, Roppongi, Tokyo, Japan), It is important for radiation risk estimation to study the "adaptive response" triggered by low-dose ionizing radiation. In this study, we tried to detect the genetic influences of low-dose (2.5 approximately 10 cGy) X-ray pre-irradiation through the window of adaptive response. The genetic changes on the chromosome after the challenging dose of X-ray (2 Gy) were analyzed by the LOH (Loss of heterozygosity) detection system, which we have already established with human lymphoblastoid cell TK6. The observed adaptive-response can be explained by the suppression of non-LOH mutations, most of which are considered to be point mutations. These results strongly suggest that the genetic influences of space environmental radiation can be estimated from the data of space experiments assuming such radiation exposure as the trigger of adaptive response., 形態: カラー図版あり, 共催: 日本学術会議, Physical characteristics: Original contains color illustrations, Meeting sponsors: The Science Council of Japan, The Institute of Space and Astronautical Science, Japan Aerospace Exploration Agency (ISAS)(JAXA), 資料番号: AA0064113064},
 publisher = {宇宙航空研究開発機構宇宙科学研究本部, Institute of Space and Astronautical Science, Japan Aerospace Exploration Agency (JAXA)},
 title = {宇宙環境放射線影響を検出するために適応応答は利用できるか？},
 volume = {22},
 year = {2006}
}