{"created":"2023-06-20T14:46:08.028041+00:00","id":13681,"links":{},"metadata":{"_buckets":{"deposit":"6fb88fef-e59e-4877-bb80-31c5a76cc280"},"_deposit":{"created_by":1,"id":"13681","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"13681"},"status":"published"},"_oai":{"id":"oai:jaxa.repo.nii.ac.jp:00013681","sets":["1543:1633:1645","1887:1891"]},"author_link":["125268","125255","125256","125258","125261","125271","125269","125263","125270","125264","125262","125265","125266","125254","125267","125260","125259","125257"],"item_5_alternative_title_2":{"attribute_name":"その他のタイトル(英)","attribute_value_mlt":[{"subitem_alternative_title":"An Application of Adaptive Response for Detection of Space Environmental Radiation Effects"}]},"item_5_biblio_info_10":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2006-03","bibliographicIssueDateType":"Issued"},"bibliographicVolumeNumber":"22","bibliographic_titles":[{"bibliographic_title":"宇宙利用シンポジウム"},{"bibliographic_title":"Space Utilization Research: Proceedings of Space Utilization Symposium","bibliographic_titleLang":"en"}]}]},"item_5_description_14":{"attribute_name":"会議概要(会議名, 開催地, 会期, 主催者等)","attribute_value_mlt":[{"subitem_description":"第22回宇宙利用シンポジウム(2006年1月17日-19日, 日本学術会議6階会議室 六本木、東京)","subitem_description_type":"Other"}]},"item_5_description_15":{"attribute_name":"会議概要(会議名, 開催地, 会期, 主催者等)(英)","attribute_value_mlt":[{"subitem_description":"The Twenty-second Space Utilization Symposium (January 17-19, 2006: Science Council of Japan, Roppongi, Tokyo, Japan)","subitem_description_type":"Other"}]},"item_5_description_17":{"attribute_name":"抄録(英)","attribute_value_mlt":[{"subitem_description":"It is important for radiation risk estimation to study the \"adaptive response\" triggered by low-dose ionizing radiation. In this study, we tried to detect the genetic influences of low-dose (2.5 approximately 10 cGy) X-ray pre-irradiation through the window of adaptive response. The genetic changes on the chromosome after the challenging dose of X-ray (2 Gy) were analyzed by the LOH (Loss of heterozygosity) detection system, which we have already established with human lymphoblastoid cell TK6. The observed adaptive-response can be explained by the suppression of non-LOH mutations, most of which are considered to be point mutations. These results strongly suggest that the genetic influences of space environmental radiation can be estimated from the data of space experiments assuming such radiation exposure as the trigger of adaptive response.","subitem_description_type":"Other"}]},"item_5_description_18":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"形態: カラー図版あり","subitem_description_type":"Other"},{"subitem_description":"共催: 日本学術会議","subitem_description_type":"Other"}]},"item_5_description_19":{"attribute_name":"内容記述(英)","attribute_value_mlt":[{"subitem_description":"Physical characteristics: Original contains color illustrations","subitem_description_type":"Other"},{"subitem_description":"Meeting sponsors: The Science Council of Japan, The Institute of Space and Astronautical Science, Japan Aerospace Exploration Agency (ISAS)(JAXA)","subitem_description_type":"Other"}]},"item_5_description_32":{"attribute_name":"資料番号","attribute_value_mlt":[{"subitem_description":"資料番号: AA0064113064","subitem_description_type":"Other"}]},"item_5_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"宇宙航空研究開発機構宇宙科学研究本部"}]},"item_5_publisher_9":{"attribute_name":"出版者(英)","attribute_value_mlt":[{"subitem_publisher":"Institute of Space and Astronautical Science, Japan Aerospace Exploration Agency (JAXA)"}]},"item_5_source_id_24":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AN10324210","subitem_source_identifier_type":"NCID"}]},"item_5_text_6":{"attribute_name":"著者所属","attribute_value_mlt":[{"subitem_text_value":"理化学研究所"},{"subitem_text_value":"理化学研究所"},{"subitem_text_value":"理化学研究所"},{"subitem_text_value":"理化学研究所"},{"subitem_text_value":"理化学研究所"},{"subitem_text_value":"国立医薬品食品衛生研究所"},{"subitem_text_value":"宇宙航空研究開発機構宇宙科学研究本部ISS科学プロジェクト室"},{"subitem_text_value":"日本宇宙フォーラム"},{"subitem_text_value":"日本宇宙フォーラム"}]},"item_5_text_7":{"attribute_name":"著者所属(英)","attribute_value_mlt":[{"subitem_text_language":"en","subitem_text_value":"Institute of Physical and Chemical Research (RIKEN)"},{"subitem_text_language":"en","subitem_text_value":"Institute of Physical and Chemical Research (RIKEN)"},{"subitem_text_language":"en","subitem_text_value":"Institute of Physical and Chemical Research (RIKEN)"},{"subitem_text_language":"en","subitem_text_value":"Institute of Physical and Chemical Research (RIKEN)"},{"subitem_text_language":"en","subitem_text_value":"Institute of Physical and Chemical Research (RIKEN)"},{"subitem_text_language":"en","subitem_text_value":"National Institure of Health Sciences"},{"subitem_text_language":"en","subitem_text_value":"ISS Science Project Office, Institute of Space and Astronautical Science, Japan Aerospace Exploration Agency (JAXA)(ISAS)"},{"subitem_text_language":"en","subitem_text_value":"Life Science Research Group, Space Utilization Promotion Department,Japan Space Forum"},{"subitem_text_language":"en","subitem_text_value":"Life Science Research Group, Space Utilization Promotion Department,Japan Space Forum"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"谷田貝, 文夫"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"梅林, 志浩"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"菅沢, 薫"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"花岡, 文雄"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"岩木, 正哉"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"本間, 正充"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"石岡, 憲昭"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"嶋津, 徹"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"鈴木, ひろみ"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Yatagai, Fumio","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Umebayashi, Yukihiro","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Sugasawa, Kaoru","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Hanaoka, Fumio","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Iwaki, Masaya","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Honma, Masamitsu","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Ishioka, Noriaki","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Shimazu, Toru","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Suzuki, Hiromi","creatorNameLang":"en"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-01-20"}],"displaytype":"detail","filename":"64113064.pdf","filesize":[{"value":"323.5 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