@inproceedings{oai:jaxa.repo.nii.ac.jp:00013702, author = {東端, 晃 and 香川, 弘昭 and 本田, 修二 and 東谷, 篤志 and 石岡, 憲昭 and Higashibata, Akira and Kagawa, Hiroaki and Honda, Shuji and Higashitani, Atsushi and Ishioka, Noriaki}, book = {宇宙利用シンポジウム, Space Utilization Research: Proceedings of Space Utilization Symposium}, month = {Mar}, note = {第22回宇宙利用シンポジウム(2006年1月17日-19日, 日本学術会議6階会議室 六本木、東京), The Twenty-second Space Utilization Symposium (January 17-19, 2006: Science Council of Japan, Roppongi, Tokyo, Japan), International Caenorhabditis elegans Experiment-1 (ICE-First) was carried out using Russian Soyuz from April 19 to 30, 2004. JAXA participated in this international cooperative experiment, and acquired the flight samples of C. elegans. JAXA organized the research team and focuses on the following investigations: 1) the role of signal transduction regarding small G protein, Rho, in a gravity sensing mechanism and neural development, 2) whether meiotic chromosomal dynamics and apoptosis in the germ cells are carried out under microgravity condition, 3) the effects of microgravity on cell migration and muscle development, 4) how microgravity affect the aging process. The post flight analyses of above investigations are in progress. In this manuscript, we would like to introduce the ICE-First mission., 共催: 日本学術会議, Meeting sponsors: The Science Council of Japan, The Institute of Space and Astronautical Science, Japan Aerospace Exploration Agency (ISAS)(JAXA), 資料番号: AA0064113085}, publisher = {宇宙航空研究開発機構宇宙科学研究本部, Institute of Space and Astronautical Science, Japan Aerospace Exploration Agency (JAXA)}, title = {線虫国際共同実験(ICE-First)の概要および成果について}, volume = {22}, year = {2006} }