@inproceedings{oai:jaxa.repo.nii.ac.jp:00013774, author = {行徳, 淳一郎 and 村上, 直子 and 高沖, 宗夫 and Gyotoku, Junichiro and Murakami, Naoko and Takaoki, Muneo}, book = {宇宙利用シンポジウム 第21回 平成16年度, Space Utilization Research: Proceedings of the Twenty-first Space Utilization Symposium}, month = {Mar}, note = {Fluid Flow is one of the most potent mechanical stimulators for bone cells. Recently it is suggested that primary cilia along with ion channels and related molecules play roles in the flow detection in kidney epithelial cells. A question if there is any similarity between kidney cells and bone cells in their flow detection mechanisms arises. Cultured osteoblastic cell line MC3T3-E1 expressed primary cilia. The cells responded to fluid flow, generated by manual rocking of flasks, and expressed c-fos gene. The cells were found to respond not only the flow but also cooling of the culture fluid. It was suggested that bone and kidney cells might share similar mechanisms in flow detection., 資料番号: AA0048095045}, pages = {201--204}, publisher = {宇宙航空研究開発機構宇宙科学研究本部, Institute of Space and Astronautical Science, Japan Aerospace Exploration Agency (JAXA/ISAS)}, title = {機械刺激による骨芽細胞の活性化機構}, year = {2005} }