@inproceedings{oai:jaxa.repo.nii.ac.jp:00013806, author = {赤松, 幹樹 and 塚本, 浩子 and 井上, かず子 and 林, 和彦 and 福永, 哲夫 and 福岡, 秀興 and Akamatsu, Motoki and Tsukamoto, Hiroko and Inoue, Kazuko and Hayashi, Kazuhiko and Fukunaga, Tetsuo and Fukuoka, Hideoki}, book = {宇宙利用シンポジウム 第20回 平成15年度, Space Utilization Research: Proceedings of the Twentieth Space Utilization Symposium}, month = {Mar}, note = {To clarify the pathophysiology of bone loss and develop a prevention method, the head-down tilting bed rest (HDT-BR) experiment was performed. Twelve healthy males, for 20 days of - six degrees HDT-BR experiment with previous and subsequent controlled periods of 5 days. This experiment induced two-typed bone metabolism. In one group, the bone metabolic markers (TrACP, BALP, PICP) respectively increased simultaneously, and in another showed no change. RT-PCR disclosed 5 to 6 times higher amount of IL-6 and Ca sensing receptor gene expression during HDT-BR., 資料番号: AA0046917001}, pages = {1--2}, publisher = {宇宙航空研究開発機構宇宙科学研究本部, Institute of Space and Astronautical Science, Japan Aerospace Exploration Agency (JAXA/ISAS)}, title = {Metabolic turnover of bone induced by microgravity in head-down tilting bed rest}, year = {2004} }