{"created":"2023-06-20T14:46:15.311724+00:00","id":13807,"links":{},"metadata":{"_buckets":{"deposit":"2925e71f-6bf3-4cb7-8fc0-1ae7ff4bfe5f"},"_deposit":{"created_by":1,"id":"13807","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"13807"},"status":"published"},"_oai":{"id":"oai:jaxa.repo.nii.ac.jp:00013807","sets":["1543:1633:1647","1887:1891"]},"author_link":["126786","126787","126788","126785","126783","126784","126782","126789"],"item_5_alternative_title_2":{"attribute_name":"その他のタイトル（英）","attribute_value_mlt":[{"subitem_alternative_title":"Modulation of cell mutability by serum factors from volunteers who experienced head-down-tilt bed rest"}]},"item_5_biblio_info_10":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2004-03","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"4","bibliographicPageStart":"3","bibliographic_titles":[{"bibliographic_title":"宇宙利用シンポジウム　第20回　平成15年度"},{"bibliographic_title":"Space Utilization Research: Proceedings of the Twentieth Space Utilization Symposium","bibliographic_titleLang":"en"}]}]},"item_5_description_17":{"attribute_name":"抄録（英）","attribute_value_mlt":[{"subitem_description":"Head-down-tilt bed rest (BR) is utilized to mimic a microgravity environment. In this study, it was examined whether the modulating activity of serum factors on cell mutability was changed in seventeen volunteers subjected to BR. For comparison, serum was comparatively obtained from seven volunteers who experienced the parabolic flight (PF). Cultured human cells were treated with serum and then irradiated with UV or X-ray. Mutagenicity was estimated by identification of K-ras codon 12 base substitution mutation, following PCR and differential dot-blot hybridization. Modulating activity was detected in one sample from each of post-BR and post-PF serum.","subitem_description_type":"Other"}]},"item_5_description_32":{"attribute_name":"資料番号","attribute_value_mlt":[{"subitem_description":"資料番号: AA0046917002","subitem_description_type":"Other"}]},"item_5_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"宇宙航空研究開発機構宇宙科学研究本部"}]},"item_5_publisher_9":{"attribute_name":"出版者（英）","attribute_value_mlt":[{"subitem_publisher":"Institute of Space and Astronautical Science, Japan Aerospace Exploration Agency (JAXA/ISAS)"}]},"item_5_text_6":{"attribute_name":"著者所属","attribute_value_mlt":[{"subitem_text_value":"千葉大学 大学院医学研究院"},{"subitem_text_value":"千葉大学 大学院医学研究院"},{"subitem_text_value":"東京大学 大学院医学系研究科"},{"subitem_text_value":"千葉大学 大学院医学研究院"}]},"item_5_text_7":{"attribute_name":"著者所属（英）","attribute_value_mlt":[{"subitem_text_language":"en","subitem_text_value":"Chiba University Graduate School of Medicine"},{"subitem_text_language":"en","subitem_text_value":"Chiba University Graduate School of Medicine"},{"subitem_text_language":"en","subitem_text_value":"University of Tokyo Graduate School of Medicine"},{"subitem_text_language":"en","subitem_text_value":"Chiba University Graduate School of Medicine"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"菅谷, 茂"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"喜多, 和子"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"福岡, 秀興"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"鈴木, 信夫"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Sugaya, Shigeru","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Kita, Kazuko","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Fukuoka, Hideoki","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Suzuki, Nobuo","creatorNameLang":"en"}],"nameIdentifiers":[{}]}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"ヒト血清","subitem_subject_scheme":"Other"},{"subitem_subject":"ヘッドダウンチルト","subitem_subject_scheme":"Other"},{"subitem_subject":"ベッドレスト","subitem_subject_scheme":"Other"},{"subitem_subject":"微小重力","subitem_subject_scheme":"Other"},{"subitem_subject":"培養ヒト細胞","subitem_subject_scheme":"Other"},{"subitem_subject":"突然変異","subitem_subject_scheme":"Other"},{"subitem_subject":"パラボリックフライト","subitem_subject_scheme":"Other"},{"subitem_subject":"X線照射","subitem_subject_scheme":"Other"},{"subitem_subject":"human serum","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"head down tilt","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"bed rest","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"microgravity","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"cultured human cell","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"mutation","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"parabolic flight","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"X-ray irradiation","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"conference paper","resourceuri":"http://purl.org/coar/resource_type/c_5794"}]},"item_title":"ベッドレスト前後でのヒト血清に含まれる変異調節活性の調査","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"ベッドレスト前後でのヒト血清に含まれる変異調節活性の調査"}]},"item_type_id":"5","owner":"1","path":["1647","1891"],"pubdate":{"attribute_name":"公開日","attribute_value":"2015-03-26"},"publish_date":"2015-03-26","publish_status":"0","recid":"13807","relation_version_is_last":true,"title":["ベッドレスト前後でのヒト血清に含まれる変異調節活性の調査"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-06-21T05:44:29.446210+00:00"}