{"created":"2023-06-20T14:46:15.706196+00:00","id":13813,"links":{},"metadata":{"_buckets":{"deposit":"b56d3905-9ba3-497f-9f31-c3d31a852c7e"},"_deposit":{"created_by":1,"id":"13813","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"13813"},"status":"published"},"_oai":{"id":"oai:jaxa.repo.nii.ac.jp:00013813","sets":["1543:1633:1647","1887:1891"]},"author_link":["126839","126833","126826","126832","126837","126830","126835","126838","126827","126834","126829","126840","126841","126836","126828","126831"],"item_5_alternative_title_2":{"attribute_name":"その他のタイトル（英）","attribute_value_mlt":[{"subitem_alternative_title":"Adaptation for gravity and stress protein"}]},"item_5_biblio_info_10":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2004-03","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"23","bibliographicPageStart":"21","bibliographic_titles":[{"bibliographic_title":"宇宙利用シンポジウム　第20回　平成15年度"},{"bibliographic_title":"Space Utilization Research: Proceedings of the Twentieth Space Utilization Symposium","bibliographic_titleLang":"en"}]}]},"item_5_description_17":{"attribute_name":"抄録（英）","attribute_value_mlt":[{"subitem_description":"A cell, the smallest unit of life, has some principles of a system to develop tension, which needs fulcrum, depending on energy consumption and supply. The fulcrum is extracellular matrix (ECM) for a cell. Most sHSPs constitutively express in slow muscle cells and contribute to developmental reorganization of various cell systems as well as responding to environmental stresses. Gravity and mechanical stress may influence cell architecture, so the increase and/or decrease of mechanical stress may induce molecular chaperones to maintain dynamics of solid system cytoskeleton inside of the cell and ECM protein like collagen protein outside of the cell. Similar to the changes of alpha-B-crystallin in atrophied soleus muscle under hindlimb suspension, HSP47 decreased with HS and increased after 3-G centrifugation. The effect of gravity clearly appears in tonic type of tension development, observed in slow skeletal muscle cells and cardiac myocyte. Dynamic property is produced and maintained with tonic tension development, in which tension development is realized by two different phases of contractions and relaxation in striated muscles. Former is consisted of the interaction of myosin and actin filament, and probably latter microtubule extension. Alpha-B-crystallin may work as molecular chaperone for tubulin/microtubule dynamics, so dynamic images of GFP-alpha-B-crystallin transfected by adeno virus vector was examined by time-lapse video system. Striated patterns of GFP-alpha-B-crystallin were obtained in beating myocyte. This suggest that alpha-B-crystallin may associate with protein complexes around probably Z/I bands receiving mechanical stress induced through contraction/relaxation cycles.","subitem_description_type":"Other"}]},"item_5_description_32":{"attribute_name":"資料番号","attribute_value_mlt":[{"subitem_description":"資料番号: AA0046917008","subitem_description_type":"Other"}]},"item_5_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"宇宙航空研究開発機構宇宙科学研究本部"}]},"item_5_publisher_9":{"attribute_name":"出版者（英）","attribute_value_mlt":[{"subitem_publisher":"Institute of Space and Astronautical Science, Japan Aerospace Exploration Agency (JAXA/ISAS)"}]},"item_5_text_6":{"attribute_name":"著者所属","attribute_value_mlt":[{"subitem_text_value":"東京大学 大学院総合文化研究科"},{"subitem_text_value":"東京大学 大学院総合文化研究科"},{"subitem_text_value":"東京大学 大学院総合文化研究科"},{"subitem_text_value":"東京大学 大学院総合文化研究科"},{"subitem_text_value":"東京大学 大学院総合文化研究科"},{"subitem_text_value":"東京大学 大学院総合文化研究科"},{"subitem_text_value":"東京大学 大学院総合文化研究科"},{"subitem_text_value":"東京大学 大学院総合文化研究科"}]},"item_5_text_7":{"attribute_name":"著者所属（英）","attribute_value_mlt":[{"subitem_text_language":"en","subitem_text_value":"University of Tokyo Graduate School of Arts and Sciences"},{"subitem_text_language":"en","subitem_text_value":"University of Tokyo Graduate School of Arts and Sciences"},{"subitem_text_language":"en","subitem_text_value":"University of Tokyo Graduate School of Arts and Sciences"},{"subitem_text_language":"en","subitem_text_value":"University of Tokyo Graduate School of Arts and Sciences"},{"subitem_text_language":"en","subitem_text_value":"University of Tokyo Graduate School of Arts and Sciences"},{"subitem_text_language":"en","subitem_text_value":"University of Tokyo Graduate School of Arts and Sciences"},{"subitem_text_language":"en","subitem_text_value":"University of Tokyo Graduate School of Arts and Sciences"},{"subitem_text_language":"en","subitem_text_value":"University of Tokyo Graduate School of Arts and Sciences"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"跡見, 順子"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"大戸, 恵理"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"藤田, 義信"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"桜井, 隆史"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"小黒, 麻美"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"大多和, 真由美"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"新井, 留美子"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"山口, 鉄生"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Atomi, Yoriko","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Oto, Eri","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Fujita, Yoshinobu","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Sakurai, Takashi","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Oguro, Asami","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Otawa, Mayumi","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Arai, Rumiko","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Yamaguchi, Tetsuo","creatorNameLang":"en"}],"nameIdentifiers":[{}]}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"重力","subitem_subject_scheme":"Other"},{"subitem_subject":"ストレス","subitem_subject_scheme":"Other"},{"subitem_subject":"タンパク質","subitem_subject_scheme":"Other"},{"subitem_subject":"適応","subitem_subject_scheme":"Other"},{"subitem_subject":"エネルギー消費","subitem_subject_scheme":"Other"},{"subitem_subject":"後肢懸垂","subitem_subject_scheme":"Other"},{"subitem_subject":"骨格筋システム","subitem_subject_scheme":"Other"},{"subitem_subject":"細胞外マトリックス","subitem_subject_scheme":"Other"},{"subitem_subject":"gravitation","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"stress","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"protein","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"adaptation","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"energy consumption","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"hindlimb suspension","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"musculoskeletal system","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"extracellular matrix","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"conference paper","resourceuri":"http://purl.org/coar/resource_type/c_5794"}]},"item_title":"重力適応とストレスタンパク質","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"重力適応とストレスタンパク質"}]},"item_type_id":"5","owner":"1","path":["1647","1891"],"pubdate":{"attribute_name":"公開日","attribute_value":"2015-03-26"},"publish_date":"2015-03-26","publish_status":"0","recid":"13813","relation_version_is_last":true,"title":["重力適応とストレスタンパク質"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-06-21T05:44:23.881578+00:00"}