@inproceedings{oai:jaxa.repo.nii.ac.jp:00013817, author = {高沖, 宗夫 and Park, Hyekyeong and 松本, 聡 and 芝, 大 and 正木, 道子 and 行徳, 淳一郎 and Takaoki, Muneo and Park, Hyekyeong and Matsumoto, Satoshi and Shiba, Dai and Masaki, Michiko and Gyotoku, Junichiro}, book = {宇宙利用シンポジウム 第20回 平成15年度, Space Utilization Research: Proceedings of the Twentieth Space Utilization Symposium}, month = {Mar}, note = {Many differences in cellular events have been found between on-orbit cultures and ground controls. These observations suggested that cells could acquire and deal with such environmental information as gravity. However, the molecular mechanism of converting physical force into biological signals had been without any clue. Recently, ion channels have been suggested to be involved in mechanosensing in various tissues. Here, examined were some possibilities if molecular mechanisms known in other tissues work also in bones. It was observed that primary cilia and polycystins, those were reported in renal cells, were also expressed in osteoblast-like cell line. Further studies are in progress to determine if primary cilia and polycystins work as the flow detector of osteoblasts., 資料番号: AA0046917012}, pages = {31--34}, publisher = {宇宙航空研究開発機構宇宙科学研究本部, Institute of Space and Astronautical Science, Japan Aerospace Exploration Agency (JAXA/ISAS)}, title = {細胞に加わる外力を生体信号に変換する過程に関与する分子の探索}, year = {2004} }