@inproceedings{oai:jaxa.repo.nii.ac.jp:00013818,
 author = {加藤, 悠子 and 澤井, 里枝 and 最上, 善広 and 馬場, 昭次 and Kato, Yuko and Sawai, Satoe and Mogami, Yoshihiro and Baba, Shoji A.},
 book = {宇宙利用シンポジウム　第20回　平成15年度, Space Utilization Research: Proceedings of the Twentieth Space Utilization Symposium},
 month = {Mar},
 note = {It has been reported that Paramecium proliferates slower when cultured under hypergravity. In order to gain an insight into the mechanism underlying the sensitivity to hypergravity, the proliferation under hypergravity was compared with that under lowering temperature or reduced nourishment, where cell proliferation rate is known to be reduced. Proliferation experiments was conducted under different conditions with three variables; gravity, temperature, and nourishment. In each experiment, control cells were grown under 1 G at 24 C with 100 percent nourishment through three experiments. In order to assess the proliferation under different conditions, the kinetic parameters of proliferation were obtained through a numerical analysis based the least squares fitting of the logistic growth equation. Maximum proliferation rate was reduced under hypergravity, lowering temperature and reduced nourishment. Saturation density was maintained under lowering temperature, while those were lower under hypergravity and reduced nourishment. Logistic parameter which was maintained under hypergravity became smaller under lowering temperature, and larger under reduced nourishment. It was also reported that hypergravity reduced the cell size of Paramecium. The maximum cell volume significantly decreased under hypergravity, while it tended to increase under lowering temperature and decrease under reduced nourishment. These results indicate that the mechanism of reduced proliferation rate under hypergravity is different from those under lowering temperature and reduced nourishment., 資料番号: AA0046917013},
 pages = {35--38},
 publisher = {宇宙航空研究開発機構宇宙科学研究本部, Institute of Space and Astronautical Science, Japan Aerospace Exploration Agency (JAXA/ISAS)},
 title = {Effects of hypergravity on the proliferation and morphology of paramecium: Comparison with those of lowering temperature and reduced nourishment},
 year = {2004}
}