@inproceedings{oai:jaxa.repo.nii.ac.jp:00013831,
 author = {加納, まゆみ and 三浦, ゆり and 戸田, 年総 and 浦野, 四郎 and 鈴木, 捷三 and Kano, Mayumi and Miura, Yuri and Toda, Toshifusa and Urano, Shiro and Suzuki, Shozo},
 book = {宇宙利用シンポジウム　第20回　平成15年度, Space Utilization Research: Proceedings of the Twentieth Space Utilization Symposium},
 month = {Mar},
 note = {Reactive oxygen species induced by radiation such as X-rays give various types of oxidative damage. However, when radiation dose is low, it causes stimulative effects on cells like the radiation adaptive response for cell growth. To study the variant expressions of proteins caused by a high or low radiation dose, the effect of X-rays on the expression of proteins in cultured glial cells was examined by proteome analysis. When glial cells were exposed to a high dose of 5 Gy, the relative abundance of 2 protein spots changed on 2-D gels. On the other hand, when cells were exposed to a low dose of 0.1 Gy, the relative abundance of one protein spot, different from one induced by 5 Gy, changed on 2-D gels. These protein spots were identified by MALDI-TOF mass spectrometry after digestion by trypsin. One of 2 spots which were changed by 5 Gy was identified as peroxiredoxin 2, and it increased with time until at least 24 hours after irradiation. It was also examined whether these protein spots would change by aging., 資料番号: AA0046917026},
 pages = {76--79},
 publisher = {宇宙航空研究開発機構宇宙科学研究本部, Institute of Space and Astronautical Science, Japan Aerospace Exploration Agency (JAXA/ISAS)},
 title = {X線照射による細胞応答とその加齢変化のプロテオーム解析},
 year = {2004}
}