{"created":"2023-06-20T14:46:25.246845+00:00","id":13963,"links":{},"metadata":{"_buckets":{"deposit":"a084b3b2-1d12-4d56-a758-3a64dc3ad47e"},"_deposit":{"created_by":1,"id":"13963","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"13963"},"status":"published"},"_oai":{"id":"oai:jaxa.repo.nii.ac.jp:00013963","sets":["1543:1633:1648","1887:1891"]},"author_link":["128200","128195","128197","128202","128196","128201","128203","128198","128199","128194"],"item_5_alternative_title_2":{"attribute_name":"その他のタイトル（英）","attribute_value_mlt":[{"subitem_alternative_title":"Molecular mechanism of the protein crystal growth in space"}]},"item_5_biblio_info_10":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2003-02","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"200","bibliographicPageStart":"197","bibliographic_titles":[{"bibliographic_title":"宇宙利用シンポジウム　第19回　平成14年度"},{"bibliographic_title":"Space Utilization Research: Proceedings of the Nineteenth Space Utilization Symposium","bibliographic_titleLang":"en"}]}]},"item_5_description_17":{"attribute_name":"抄録（英）","attribute_value_mlt":[{"subitem_description":"Growth mechanism of protein single crystal is not essentially influenced by the gravity because the crystal growth in a microgravity field in space proceeds by the same way on the earth. However, the unit cell volume of the space-grown crystals was slightly smaller than that of the earth-grown ones. Two forms of orthorhombic crystals, form 1 and form 2, of hen egg-white lysozyme (EC 3.2.1.17, HEWL) appeared under the conditions of different growth temperature. Comparison of the molecular packing of these two different crystal forms showed that both crystal forms possessed a common molecular unit consisted of two molecules in the asymmetric unit. However, the molecular packing was quite different from each other. Evaluating Van der Waals energy for the intermolecular interaction, a molecular mechanism of crystal growth of HEWL orthorhombic crystal was proposed. Further, it was emphasized that during the crystal growth protein molecule was incorporated into the nuclei preferentially to complete the molecular unit, and that not a mass more than a dimmer but one protein molecule was a growth unit. Transfer of protein molecules under the microgravity field is controlled by the diffusion transport instead of the convection transport on earth so that the orientation of the protein molecule in the crystal may be improved, taking into consideration that the exact orientation of protein molecule is governed by the selective interactions of the molecules on the crystal surface.","subitem_description_type":"Other"}]},"item_5_description_32":{"attribute_name":"資料番号","attribute_value_mlt":[{"subitem_description":"資料番号: AA0045438056","subitem_description_type":"Other"}]},"item_5_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"宇宙科学研究所"}]},"item_5_publisher_9":{"attribute_name":"出版者（英）","attribute_value_mlt":[{"subitem_publisher":"The Institute of Space and Astronautical Science (ISAS)"}]},"item_5_text_6":{"attribute_name":"著者所属","attribute_value_mlt":[{"subitem_text_value":"京都大学 大学院農学研究科"},{"subitem_text_value":"京都大学 大学院農学研究科"},{"subitem_text_value":"名古屋大学 大学院工学研究科"},{"subitem_text_value":"名古屋大学 大学院工学研究科"},{"subitem_text_value":"横浜市立大学 大学院総合理学研究科"}]},"item_5_text_7":{"attribute_name":"著者所属（英）","attribute_value_mlt":[{"subitem_text_language":"en","subitem_text_value":"Kyoto University Graduate School of Agriculture"},{"subitem_text_language":"en","subitem_text_value":"Kyoto University Graduate School of Agriculture"},{"subitem_text_language":"en","subitem_text_value":"Nagoya University Graduate School of Engineering"},{"subitem_text_language":"en","subitem_text_value":"Nagoya University Graduate School of Engineering"},{"subitem_text_language":"en","subitem_text_value":"Yokohama City University Graduate School of Integrated Science"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"相原, 茂夫"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"廣瀬, 正明"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"鈴木, 淳巨"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"山根, 隆"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"木寺, 詔紀"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Aihara, Shigeo","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Hirose, Masaaki","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Suzuki, Atsuo","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Yamane, Takashi","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Kidera, Akinori","creatorNameLang":"en"}],"nameIdentifiers":[{}]}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"タンパク質結晶成長","subitem_subject_scheme":"Other"},{"subitem_subject":"宇宙環境","subitem_subject_scheme":"Other"},{"subitem_subject":"単結晶","subitem_subject_scheme":"Other"},{"subitem_subject":"微小重力","subitem_subject_scheme":"Other"},{"subitem_subject":"分子間力","subitem_subject_scheme":"Other"},{"subitem_subject":"Van der Waals力","subitem_subject_scheme":"Other"},{"subitem_subject":"分子機構","subitem_subject_scheme":"Other"},{"subitem_subject":"拡散","subitem_subject_scheme":"Other"},{"subitem_subject":"protein crystal growth","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"aerospace environment","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"single crystal","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"microgravity","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"intermolecular force","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Van der Waals force","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"molecular mechanism","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"diffusion","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"conference paper","resourceuri":"http://purl.org/coar/resource_type/c_5794"}]},"item_title":"宇宙におけるタンパク質結晶成長の分子メカニズム","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"宇宙におけるタンパク質結晶成長の分子メカニズム"}]},"item_type_id":"5","owner":"1","path":["1648","1891"],"pubdate":{"attribute_name":"公開日","attribute_value":"2015-03-26"},"publish_date":"2015-03-26","publish_status":"0","recid":"13963","relation_version_is_last":true,"title":["宇宙におけるタンパク質結晶成長の分子メカニズム"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-06-21T05:42:01.717066+00:00"}