{"created":"2023-06-20T15:10:07.731551+00:00","id":39721,"links":{},"metadata":{"_buckets":{"deposit":"678dd627-e830-42a4-8611-60a0183c123a"},"_deposit":{"created_by":1,"id":"39721","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"39721"},"status":"published"},"_oai":{"id":"oai:jaxa.repo.nii.ac.jp:00039721","sets":["1887:1893","1896:1898:1933:1934"]},"author_link":["500087","500081","500084","500080","500086","500085","500089","500082","500083","500088"],"item_3_alternative_title_2":{"attribute_name":"その他のタイトル（英）","attribute_value_mlt":[{"subitem_alternative_title":"Dosimetry measurement of heavy particle beam in a space shuttle and investigation of its effect on living organisms (Radiation): Effect of microgravity on DNA repair activity of bacterium Deinococcus radiodurans"}]},"item_3_biblio_info_10":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"1996-03-15","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"241","bibliographicPageStart":"235","bibliographic_titles":[{"bibliographic_title":"宇宙開発事業団技術報告"},{"bibliographic_title":"NASDA Technical Memorandum","bibliographic_titleLang":"en"}]}]},"item_3_description_16":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"宇宙線の影響を無視できるように、極めて耐放射線性の強い細菌Deinococcus radioduransを使用して、DNA修復機構に対する微小重力の影響を、IML-2ミッション(STS-65,7月8-23日、1994年)で調査した。宇宙飛行前に細胞を凍結乾燥し、コバルト60ガンマ線照射を線量12kGyまでおこなった。このミッションのほぼ終期に、修復過程を活性化するため細胞を液体倍地と混合し、放射線により誘導されたDNA損傷を修復させるために、スペースラボの室温で11時間培養した。宇宙で活性化された細胞の生存は地上対照に比べると有意に高く、このことはこの細菌のDNA修復機構が微小重力下で促進されていることを示唆している。","subitem_description_type":"Abstract"}]},"item_3_description_17":{"attribute_name":"抄録（英）","attribute_value_mlt":[{"subitem_description":"Effect of microgravity on DNA (Deoxyribonucleic Acid) repair system was examined on the IML (International Microgravity Laboratory)-2 mission (STS-65, July 8-23, 1994) using extremely radioresistant bacterium Deinococcus radiodurans so that influence of cosmic radiation can be neglected. Cells were lyophilized and exposed to Co-60 gamma-rays with doses up to 12 kGy before the space flight. Almost at the end of the mission, the cells were mixed on board with liquid nutrient medium to activate the repair process, then incubated at room temperature of the spacelab for 11 hrs to allow the repair of the radiation-induced DNA damages. Afterwards the cells were stored at 4 C until landing. The survival of the cells activated in space increased significantly compared with the ground controls, suggesting that DNA repair system of this bacterium was enhanced under microgravity.","subitem_description_type":"Other"}]},"item_3_description_32":{"attribute_name":"資料番号","attribute_value_mlt":[{"subitem_description":"資料番号: AA0000271012","subitem_description_type":"Other"}]},"item_3_description_33":{"attribute_name":"レポート番号","attribute_value_mlt":[{"subitem_description":"レポート番号: NASDA-TMR-960004","subitem_description_type":"Other"}]},"item_3_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"宇宙開発事業団"}]},"item_3_publisher_9":{"attribute_name":"出版者（英）","attribute_value_mlt":[{"subitem_publisher":"National Space Development Agency of Japan (NASDA)"}]},"item_3_source_id_21":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"1345-7888","subitem_source_identifier_type":"ISSN"}]},"item_3_source_id_24":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AN00364784","subitem_source_identifier_type":"NCID"}]},"item_3_text_6":{"attribute_name":"著者所属","attribute_value_mlt":[{"subitem_text_value":"日本原子力研究所 高崎研究所"},{"subitem_text_value":"日本原子力研究所 高崎研究所"},{"subitem_text_value":"日本原子力研究所 高崎研究所"},{"subitem_text_value":"PL学園女子短期大学"},{"subitem_text_value":"宇宙開発事業団 宇宙実験グループ"}]},"item_3_text_7":{"attribute_name":"著者所属（英）","attribute_value_mlt":[{"subitem_text_language":"en","subitem_text_value":"Japan Atomic Energy Research Institute Takasaki Radiation Chemistry Research Establishment"},{"subitem_text_language":"en","subitem_text_value":"Japan Atomic Energy Research Institute Takasaki Radiation Chemistry Research Establishment"},{"subitem_text_language":"en","subitem_text_value":"Japan Atomic Energy Research Institute Takasaki Radiation Chemistry Research Establishment"},{"subitem_text_language":"en","subitem_text_value":"PL Gakuen Women's Junior College"},{"subitem_text_language":"en","subitem_text_value":"National Space Development Agency of Japan Space Experiment Group"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"渡辺, 宏"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"小林, 泰彦"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"菊地, 正博"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"原田, 和樹"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"長岡, 俊治"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Watanabe, Hiroshi","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Kobayashi, Yasuhiko","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Kikuchi, Masahiro","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Harada, Kazuki","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Nagaoka, Shunji","creatorNameLang":"en"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-02-10"}],"displaytype":"detail","filename":"00271012.pdf","filesize":[{"value":"623.7 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"00271012.pdf","url":"https://jaxa.repo.nii.ac.jp/record/39721/files/00271012.pdf"},"version_id":"f7b23dac-41b7-44a2-bc8c-3949de03eb3f"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"DNA修復機構","subitem_subject_scheme":"Other"},{"subitem_subject":"耐放射線性細菌","subitem_subject_scheme":"Other"},{"subitem_subject":"微小重力","subitem_subject_scheme":"Other"},{"subitem_subject":"液体培地","subitem_subject_scheme":"Other"},{"subitem_subject":"バクテリア","subitem_subject_scheme":"Other"},{"subitem_subject":"生存","subitem_subject_scheme":"Other"},{"subitem_subject":"損傷","subitem_subject_scheme":"Other"},{"subitem_subject":"重粒子線","subitem_subject_scheme":"Other"},{"subitem_subject":"生物効果","subitem_subject_scheme":"Other"},{"subitem_subject":"宇宙実験","subitem_subject_scheme":"Other"},{"subitem_subject":"線量計測","subitem_subject_scheme":"Other"},{"subitem_subject":"宇宙線","subitem_subject_scheme":"Other"},{"subitem_subject":"DNA repair system","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"radioresistant bacterium","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"microgravity","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"liquid nutrient medium","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"bacterium","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"survival","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"damage","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"heavy particle beam","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"effect on living organism","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"space experiment","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"dosimetry measurement","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"cosmic radiation","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"technical report","resourceuri":"http://purl.org/coar/resource_type/c_18gh"}]},"item_title":"宇宙船内における重粒子線による線量計測とその生物効果実験(RADIATION):D. radioduransのDNA修復能に対する微小重力の影響","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"宇宙船内における重粒子線による線量計測とその生物効果実験(RADIATION):D. radioduransのDNA修復能に対する微小重力の影響"}]},"item_type_id":"3","owner":"1","path":["1893","1934"],"pubdate":{"attribute_name":"公開日","attribute_value":"2015-03-26"},"publish_date":"2015-03-26","publish_status":"0","recid":"39721","relation_version_is_last":true,"title":["宇宙船内における重粒子線による線量計測とその生物効果実験(RADIATION):D. radioduransのDNA修復能に対する微小重力の影響"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-06-20T20:29:41.878428+00:00"}