@techreport{oai:jaxa.repo.nii.ac.jp:00039867, author = {長岡, 俊治 and 宮本, 晃 and 渡邉, 悟 and 臼井, 支朗 and 吉本, 智信 and 上野, 俊昭 and 鈴木, 啓之 and 平田, 豊 and 小嶋, 悌亮 and 山縣, 眞樹 and Nagaoka, Shunji and Miyamoto, Akira and Watanabe, Satoru and Usui, Shiro and Yoshimoto, Satonobu and Ueno, Toshiaki and Suzuki, Keisuke and Hirata, Yutaka and Kojima, Teiryo and Yamagata, Maki}, month = {Jan}, note = {この実験シリーズの目的は、宇宙機の微小重力環境下のような特殊な状況での生理的変化を予測するため、計測、データ処理および解析の新規技術を開発し改良することにある。本報告では、以下の新規適用について実験方法論および結果を評価し考察した。瞳孔光反射の計測について、重力レベルおよび被験者座位の変化に関連する瞳孔径の動的応答を計測するため新瞳孔計を使用した。脳循環の血行動態を近赤外分光計を用いて検査した。特に水平性眼球運動に対する視線運動性応答を計測するため、HMD(ヘッドマウンテッドディスプレイ)を導入し各種の視運動刺激を加えた。動揺病の度合との関連性で胃電図を取り評価した。5人の健康な成人ボランティア(男性2名、女性3名)を実験被験者として採用した。その結果として、近赤外分光計により検査した脳血液量と重力変化との間に顕著な相関関係を観測した。重力条件の変化の下での信頼性、再現性および操作性を考察した。, The aim of this series of experiments is to develop and improve new technology of measurements, data processing and analysis in order to presuppose physiological changes under specific situations such as under microgravity environment of spacecraft. In this report, the following new applications were discussed to evaluate the experiment methodology and the results. For a measurement of human pupilary light reflex, a new pupilometer was applied to measure the dynamic responses of a pupil diameter in relation to the alternation of gravity level and subject postures. Movement and state of cerebral blood circulation was examined by using a near infrared spectrophotometry. Head Mounted Display (HMD) was introduced to apply various visual stimulus to acquire optokinetic responses especially for horizontal nystagmus. Electrogastrogram was measured and evaluated with a relation to a degree of the motion sickness. Five healthy adult volunteers (two males, three females) were employed as experiment subject. As the result, the significant correlation was observed between the brain blood content and the gravitational changes examined by the near infrared spectrophotometry. Reliability, reproducibility and operationability under alternation of gravity condition were discussed., 資料番号: AA0000742004, レポート番号: NASDA-TMR-960025}, title = {生体信号計測技術の開発}, year = {1997} }