{"created":"2023-06-20T14:39:20.059006+00:00","id":6078,"links":{},"metadata":{"_buckets":{"deposit":"d6f5afb0-2099-4104-aca0-cd8d24d590bb"},"_deposit":{"created_by":1,"id":"6078","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"6078"},"status":"published"},"_oai":{"id":"oai:jaxa.repo.nii.ac.jp:00006078","sets":["1887:1893","9:789:1031:1033"]},"author_link":["30302","30301"],"item_3_alternative_title_2":{"attribute_name":"その他のタイトル（英）","attribute_value_mlt":[{"subitem_alternative_title":"Gene expression of p53-regulated genes after exposure to space environment in mammalian cultured cells"}]},"item_3_biblio_info_10":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2006-03-31","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"4","bibliographicPageStart":"1","bibliographicVolumeNumber":"JAXA-SP-05-039","bibliographic_titles":[{"bibliographic_title":"宇宙航空研究開発機構特別資料: 平成17年度ISS科学プロジェクト室放射線生物研究プロジェクト研究開発報告"},{"bibliographic_title":"JAXA Special Publication: FY2005 Research and Development Report on Radiation Biology Research Project at ISS Science Project Group","bibliographic_titleLang":"en"}]}]},"item_3_description_16":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"DNAマイクロアレイによる10,368個の遺伝子の発現解析を行うことで、宇宙放射線特有の低線量、低線量率放射線の発現誘導または抑制される遺伝子を網羅的に解析するとともに、ほ乳動物細胞の培養条件および凍結の影響についてもあわせて解析を行った。その結果、国際宇宙ステーション内の予想被曝線量(約0.2〜0.5mSv/day)においても形質発現が変動する遺伝子があることが明らかになった。","subitem_description_type":"Abstract"}]},"item_3_description_17":{"attribute_name":"抄録（英）","attribute_value_mlt":[{"subitem_description":"To identify the biological effect of low dose-rate irradiation, we analyzed the gene expression using DNA micro array. Human cultured lymphoblastoid cells TK-6 were irradiated with gamma-ray (dose-rate, 0.2 or 0.5 mGy/day; irradiation time, five days) in flask or tube bag. As results, we demonstrated that there were many kinds of genes which expressed different levels by expected doses (0.2 to 0.5 mSv/day) at ISS.","subitem_description_type":"Other"}]},"item_3_description_32":{"attribute_name":"資料番号","attribute_value_mlt":[{"subitem_description":"資料番号: AA0049800001","subitem_description_type":"Other"}]},"item_3_description_33":{"attribute_name":"レポート番号","attribute_value_mlt":[{"subitem_description":"レポート番号: JAXA-SP-05-039","subitem_description_type":"Other"}]},"item_3_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"宇宙航空研究開発機構"}]},"item_3_publisher_9":{"attribute_name":"出版者（英）","attribute_value_mlt":[{"subitem_publisher":"Japan Aerospace Exploration Agency (JAXA)"}]},"item_3_source_id_21":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"1349-113X","subitem_source_identifier_type":"ISSN"}]},"item_3_source_id_24":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AA11984031","subitem_source_identifier_type":"NCID"}]},"item_3_text_6":{"attribute_name":"著者所属","attribute_value_mlt":[{"subitem_text_value":"奈良県立医科大学 医学部　生物学教室"}]},"item_3_text_7":{"attribute_name":"著者所属（英）","attribute_value_mlt":[{"subitem_text_language":"en","subitem_text_value":"Nara Medical University Department of Biology, Medical Faculty"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"大西, 武雄"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Onishi, Takeo","creatorNameLang":"en"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-01-16"}],"displaytype":"detail","filename":"49800001.pdf","filesize":[{"value":"1.8 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"49800001.pdf","url":"https://jaxa.repo.nii.ac.jp/record/6078/files/49800001.pdf"},"version_id":"5ef2edf4-acc7-4710-b2a2-59623493ec44"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"哺乳動物","subitem_subject_scheme":"Other"},{"subitem_subject":"培養細胞","subitem_subject_scheme":"Other"},{"subitem_subject":"遺伝子発現","subitem_subject_scheme":"Other"},{"subitem_subject":"ガンマ線","subitem_subject_scheme":"Other"},{"subitem_subject":"宇宙線","subitem_subject_scheme":"Other"},{"subitem_subject":"遺伝子","subitem_subject_scheme":"Other"},{"subitem_subject":"放射線曝露","subitem_subject_scheme":"Other"},{"subitem_subject":"LET","subitem_subject_scheme":"Other"},{"subitem_subject":"航空宇宙環境","subitem_subject_scheme":"Other"},{"subitem_subject":"微小重力","subitem_subject_scheme":"Other"},{"subitem_subject":"mammal","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"cultured cell","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"gene expression","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"gamma ray","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"cosmic ray","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"gene","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"radiation exposure","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"LET","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"aerospace environment","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"microgravity","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"technical report","resourceuri":"http://purl.org/coar/resource_type/c_18gh"}]},"item_title":"ほ乳動物培養細胞における宇宙環境曝露後のp53調節遺伝子群の遺伝子発現","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"ほ乳動物培養細胞における宇宙環境曝露後のp53調節遺伝子群の遺伝子発現"}]},"item_type_id":"3","owner":"1","path":["1033","1893"],"pubdate":{"attribute_name":"公開日","attribute_value":"2015-03-26"},"publish_date":"2015-03-26","publish_status":"0","recid":"6078","relation_version_is_last":true,"title":["ほ乳動物培養細胞における宇宙環境曝露後のp53調節遺伝子群の遺伝子発現"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-06-21T08:02:34.079754+00:00"}