Department of Life Science, Graduate School of Arts and Sciences, University of Tokyo
Shimoda Marine Research Center, University of Tsukuba
Shimizu Institute of Space Physiology, Suwa Maternity Clinic
Development of Human Relation, Wako University
Department of Regulatory Physiology, Dokkyo Medical University
Department of Advanced Bioscience, Ochanomizu University
Department of Biology, Faculty of Science, Yamagata University
Department of Life Science, Graduate School of Arts and Sciences, University of Tokyo
出版者
宇宙航空研究開発機構宇宙科学研究本部
出版者（英）
Institute of Space and Astronautical Science, Japan Aerospace Exploration Agency (JAXA)
雑誌名
宇宙利用シンポジウム
雑誌名(英)
Space Utilization Research: Proceedings of Space Utilization Symposium
The Twenty-fifth Space Utilization Symposium (January 14-15, 2009: ISAS/JAXA Sagamihara, Japan)
抄録（英）
We organized a working group for studying the reproduction and continuity of life under the space environment. The aim of our project this year is to get deeper insight into the effect of gravity on reproduction. We found that suppression of body weight together with the decrease in food intake of mice under the hyper gravity, 3G, where they lost appetite. The effect was more apparent in younger mice. Hormones that reduce appetite, such as insulin and leptin were not likely to work. These results suggest that unknown complicate mechanism should be involved. We found a phenomenon that sex hormone might affect the fertilization directly via regulating the hyper activation of sperm. In addition we propose a new method for assessing the spermatogenesis activity by measuring apoptosis in spermatogenesis by means of caspase activity. This technique revealed that the spermatogenesis was suppressed by 10 G hypergravity in medaka.
宇宙環境下における生殖・継世代研究の展開: V
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